MYSM1

Gene Symbol MYSM1
Entrez Gene 114803
Alt Symbol 2A-DUB, 2ADUB
Species Human
Gene Type protein-coding
Description Myb-like, SWIRM and MPN domains 1
Other Description histone H2A deubiquitinase MYSM1|myb-like, SWIRM and MPN domain-containing protein 1
Swissprots Q7Z3G8 Q6AI53 B3KX65 Q96PX3 Q5VVJ2 Q68DD3 A8KA54
Accessions Q5VVJ2 AB067502 BAB67808 AK126835 BAG54377 AK292919 BAF85608 BC037536 BC167849 AAI67849 BX537912 CAD97896 BX648168 CR627323 CAH10370 CR749450 CAH18287 XM_006710314 XP_006710377 XM_011540573 XP_011538875 XM_011540574 XP_011538876 XR_246231 XR_946533 NM_001085487 NP_001078956
Function Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. {ECO:0000269|PubMed:17707232}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00624, ECO:0000269|PubMed:17707232}.

MYSM1 CRISPR/Cas9 KO Plasmid (h) - sc-405349 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 HDR Plasmid (h) - sc-405349-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 Double Nickase Plasmid (h) - sc-405349-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 Double Nickase Plasmid (h2) - sc-405349-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 CRISPR Activation Plasmid (h) - sc-405349-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 CRISPR Activation Plasmid (h2) - sc-405349-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 Lentiviral Activation Particles (h) - sc-405349-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 Lentiviral Activation Particles (h2) - sc-405349-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

MYSM1 siRNA (h) - sc-78930 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MYSM1 shRNA Plasmid (h) - sc-78930-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MYSM1 shRNA (h) Lentiviral Particles - sc-78930-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU053351 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14884 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14884 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MYSM1 siRNA (Human) - CRJ4386 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MYSM1 (NM_001085487.2) - SHH348536 from Creative biogene

Category siRNA
Species Reactivities Human

Human MYSM1 siRNA - orb274887 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MYSM1 shRNA Plasmid (Human) - CHJ4386 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MYSM1 miRNA 3'UTR clone - MiUTR3H-12331 from Creative biogene

Species Reactivities Human
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