SIGLEC10

Gene Symbol SIGLEC10
Entrez Gene 89790
Alt Symbol PRO940, SIGLEC-10, SLG2
Species Human
Gene Type protein-coding
Description sialic acid binding Ig-like lectin 10
Other Description sialic acid binding Ig-like lectin 10 Ig-like lectin 7|sialic acid-binding Ig-like lectin 10|siglec-like gene 2|siglec-like protein 2
Swissprots A8K1I5 F8W917 C9JM10 Q96LC7 Q96G54 Q6UXI8 Q3MIR5 Q96LC8 C9JJ33 A8K3C7
Accessions AAK40255 AAK40256 EAW72012 EAW72013 EAW72014 EAW72015 EAW72016 Q96LC7 AF301007 AAM83254 AF310233 AAK55139 AF311905 AAK92542 AK122619 BAC85493 AK289900 BAF82589 AK290542 BAF83231 AK292025 BAF84714 AK294185 BAH11692 AK303514 BAH13979 AK303717 BAH14029 AK308982 AY032685 AAK51124 AY358337 AAQ88703 BC009955 AAH09955 BC101725 AAI01726 BC143497 AAI43498 BC143500 AAI43501 XM_005259366 XP_005259423 XM_005259367 XP_005259424 XM_005259369 XP_005259426 XM_011527439 XP_011525741 NM_001171160 NM_001171156 NP_001164627 NM_001171157 NP_001164628 NM_001171158 NP_001164629 NM_001171159 NP_001164630 NM_001171161 NP_001164632 NM_033130 NP_149121
Function Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Subcellular Location Isoform 5: Secreted.
Tissue Specificity Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform 5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found at high levels and isoform 2 at lower levels in bone marrow, spleen and spinal chord. Isoform 2 is also found in brain. Isoform 4 is specifically found in natural killer cells.

Siglec-10 (S-15) - sc-240883 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Siglec-10 (N-13) - sc-240882 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Siglec-10 (N-25) - sc-130267 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Siglec-10 (N-25): sc-130267. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.

Anti-SIGLEC10 antibody - ab59942 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ab59942 at 1/50 - 1/100 dilution, staining SIGLEC10 in human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue, followed by peroxidase-conjugated secondary antibody and AEC staining.

Anti-SIGLEC10 antibody - ab112564 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-SIGLEC10 antibody (ab112564) at 1/100 dilution + HeLa Cell Lysate at 35 µg

Anti-SIGLEC10 antibody [MM090525Q3] - ab201697 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM090525Q3

Anti-SIGLEC10 antibody - C-terminal - ab198724 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling SIGLEC10 with ab198724 at 1/25 dilution.

Anti-SIGLEC10 antibody - C-terminal - ab194576 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-SIGLEC10 antibody - C-terminal (ab194576) at 1/500 dilution + HepG2 cell lysate at 50 µg

Anti-SIGLEC10 Antibody (C-Terminus, AP) - LS-C240769 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (C-Terminus, Biotin) - LS-C240771 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (C-Terminus, APC) - LS-C240770 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (C-Terminus, FITC) - LS-C240772 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa666-695, APC) - LS-C240773 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa666-695, AP) - LS-C240774 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa666-695, Biotin) - LS-C240775 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (C-Terminus, PE) - LS-C240776 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa666-695, PE) - LS-C240780 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (C-Terminus, Azide-free, HRP) - LS-C248155 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa666-695, Azide-free, HRP) - LS-C248156 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa666-695, FITC) - LS-C240777 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa571-697, FITC) - LS-C302479 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa571-697, Biotin) - LS-C300195 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa666-695) - LS-C325111 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (C-Terminus) - LS-C330127 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SIGLEC10 Antibody (aa215-264) - LS-C111255 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SIGLEC10 antibody LS-C111255 Western blot of OVCAR-3 cell lysate.
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