SIGLEC10

Gene Symbol	SIGLEC10
Entrez Gene	89790
Alt Symbol	PRO940, SIGLEC-10, SLG2
Species	Human
Gene Type	protein-coding
Description	sialic acid binding Ig-like lectin 10
Other Description	sialic acid binding Ig-like lectin 10 Ig-like lectin 7|sialic acid-binding Ig-like lectin 10|siglec-like gene 2|siglec-like protein 2
Swissprots	A8K1I5 F8W917 C9JM10 Q96LC7 Q96G54 Q6UXI8 Q3MIR5 Q96LC8 C9JJ33 A8K3C7
Accessions	AAK40255 AAK40256 EAW72012 EAW72013 EAW72014 EAW72015 EAW72016 Q96LC7 AF301007 AAM83254 AF310233 AAK55139 AF311905 AAK92542 AK122619 BAC85493 AK289900 BAF82589 AK290542 BAF83231 AK292025 BAF84714 AK294185 BAH11692 AK303514 BAH13979 AK303717 BAH14029 AK308982 AY032685 AAK51124 AY358337 AAQ88703 BC009955 AAH09955 BC101725 AAI01726 BC143497 AAI43498 BC143500 AAI43501 XM_005259366 XP_005259423 XM_005259367 XP_005259424 XM_005259369 XP_005259426 XM_011527439 XP_011525741 NM_001171160 NM_001171156 NP_001164627 NM_001171157 NP_001164628 NM_001171158 NP_001164629 NM_001171159 NP_001164630 NM_001171161 NP_001164632 NM_033130 NP_149121
Function	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Subcellular Location	Isoform 5: Secreted.
Tissue Specificity	Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform 5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found at high levels and isoform 2 at lower levels in bone marrow, spleen and spinal chord. Isoform 2 is also found in brain. Isoform 4 is specifically found in natural killer cells.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone in cloning vector - HG13765-G from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone in cloning vector - HG13934-G from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, N-His tag - HG13934-NH from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13765-ACR from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13934-ACR from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13765-NF from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13765-NM from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, C-His tag - HG13934-CH from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13765-CF from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13765-CM from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13934-NF from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13934-NY from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13934-NM from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13934-CF from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13934-CM from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, N-His tag - HG13765-NH from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13765-CY from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid - HG13765-UT from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, C-His tag - HG13765-CH from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid - HG13934-UT from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13934-CY from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13765-ACG from Sino Biological Species Human

Human SIGLEC10 transcript variant 3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13765-NY from Sino Biological Species Human

Human SIGLEC10 transcript variant 5 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13934-ACG from Sino Biological Species Human

Human Siglec-10 (NP_149121) VersaClone cDNA - RDC1466 from R&D Systems Prices $499.00 Sizes 10 µg Species Human

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