SIGLEC10

Gene Symbol	SIGLEC10
Entrez Gene	89790
Alt Symbol	PRO940, SIGLEC-10, SLG2
Species	Human
Gene Type	protein-coding
Description	sialic acid binding Ig-like lectin 10
Other Description	sialic acid binding Ig-like lectin 10 Ig-like lectin 7|sialic acid-binding Ig-like lectin 10|siglec-like gene 2|siglec-like protein 2
Swissprots	A8K1I5 F8W917 C9JM10 Q96LC7 Q96G54 Q6UXI8 Q3MIR5 Q96LC8 C9JJ33 A8K3C7
Accessions	AAK40255 AAK40256 EAW72012 EAW72013 EAW72014 EAW72015 EAW72016 Q96LC7 AF301007 AAM83254 AF310233 AAK55139 AF311905 AAK92542 AK122619 BAC85493 AK289900 BAF82589 AK290542 BAF83231 AK292025 BAF84714 AK294185 BAH11692 AK303514 BAH13979 AK303717 BAH14029 AK308982 AY032685 AAK51124 AY358337 AAQ88703 BC009955 AAH09955 BC101725 AAI01726 BC143497 AAI43498 BC143500 AAI43501 XM_005259366 XP_005259423 XM_005259367 XP_005259424 XM_005259369 XP_005259426 XM_011527439 XP_011525741 NM_001171160 NM_001171156 NP_001164627 NM_001171157 NP_001164628 NM_001171158 NP_001164629 NM_001171159 NP_001164630 NM_001171161 NP_001164632 NM_033130 NP_149121
Function	Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
Subcellular Location	Isoform 5: Secreted.
Tissue Specificity	Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform 5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found at high levels and isoform 2 at lower levels in bone marrow, spleen and spinal chord. Isoform 2 is also found in brain. Isoform 4 is specifically found in natural killer cells.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SIGLEC10 protein fragment - ab164780 from Abcam Category Protein Source Wheat germ Species Human

SIGLEC10 Antibody Blocking Peptide - LS-E4902 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIGLEC10 Antibody Blocking Peptide - LS-E18122 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Siglec-10 Protein - H00089790-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SIGLEC10-Antibody-C-term-Blocking-Peptide - BP17284b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Siglec-10 Fc Chimera, CF - 2130-SL-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

SIGLEC10 Blocking Peptide - 33R-1714 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human SIGLEC10 Protein - abx069062 from Abbexa Category Protein Source E.coli Species Human

SIGLEC10 - H00089790-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SIGLEC10 - H00089790-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10), Human - 20-8859 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

SIGLEC10 fusion protein - ag12814 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) - RPD921Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) - RPD921Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Sialic acid-binding Ig-like lectin 10(SIGLEC10) - CSB-YP842706HU CSB-EP842706HU CSB-BP842706HU CSB-MP842706HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Siglec-10 Fc Chimera Protein, CF - 2130-SL from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Human Siglec-10 (Met17-Thr546) Accession # Q96LC7 IEGRMD Human IgG 1 (Pro100-Lys330) N-terminus C-terminus Species Human

Siglec-10 Recombinant Protein Antigen - NBP1-82759PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SIGLEC10-Antibody-C-term-Blocking-Peptide - BP1628b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIGLEC10-Antibody-N-term-Blocking-Peptide - BP1628a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SIGLEC10 Peptide, Human - M34GP14238H from Creative Peptides Category Peptide Source Synthetic. Species Human

SIGLEC10 Recombinant Protein (OPCD06973) - OPCD06973 from Aviva Systems Biology Category Protein Source E.coli Species Human

Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10), Recombinant Protein - MBS2010493 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Sialic acid-binding Ig-like lectin 10 (SIGLEC10), Recombinant Protein - MBS1471491 from MyBioSource Category Protein Prices $1,325.00, $1,325.00, $1,545.00, $1,545.00, $2,190.00, $2,190.00, $2,655.00, $2,655.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Human Siglec-10 Fc Chimera Protein, CF - 2130-SL from Novus Biologicals Category Protein Prices $329.00 Sizes 50 µg Species Human

Recombinant Human SIGLEC10 protein, Mouse IgG2a Fc-tagged, low endotoxin - SIGLEC10-331H from Creative Biomart Category Protein Source HEK293 Species Human

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