Gene Symbol | GALNT4 |
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Entrez Gene | 8693 |
Alt Symbol | GALNAC-T4, GALNACT4 |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase 4 |
Other Description | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)|polypeptide GalNAc transferase 4|pp-GaNTase 4|protein-UDP acetylgalactosaminyltransferase 4 |
Swissprots | O00208 Q8N4A0 B4DMX6 B2R775 |
Accessions | CAA69875 EAW97428 Q8N4A0 AK026150 AK026438 AK312870 BAG35722 AW835269 BC036390 AAH36390 CR739813 DA109687 DQ891684 ABM82610 DQ894869 ABM85795 DQ896831 ABM87830 EU176606 ABW03407 NM_003774 NP_003765 |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates 'Thr-57' of SELPLG. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305|PubMed:9804815}; Single-pass type II membrane protein {ECO:0000305|PubMed:9804815}. |
Tissue Specificity | Ubiquitous. Highly expressed in mucous cells. {ECO:0000269|PubMed:9804815}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-T4 (P-12) - sc-107553 from Santa Cruz Biotechnology
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GalNAc-T4 (N-12) - sc-107552 from Santa Cruz Biotechnology
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GalNAc-T4 (T-14) - sc-107554 from Santa Cruz Biotechnology
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Anti-GALNT4 antibody - ab201216 from Abcam
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Anti-GALNT4 antibody - ab107497 from Abcam
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Anti-GALNT4 Antibody (aa93-120, APC) - LS-C235533 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa93-120, Biotin) - LS-C235534 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa93-120, AP) - LS-C235535 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa93-120, FITC) - LS-C235536 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa93-120, PE) - LS-C235539 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa93-120, Azide-free, HRP) - LS-C249036 from LifeSpan Bioscience
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Anti-GALNT4 Antibody - LS-C310442 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa100-128) - LS-C321543 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa360-409) - LS-C111041 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa470-519) - LS-C80731 from LifeSpan Bioscience
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Anti-GALNT4 Antibody (aa93-120) - LS-C166356 from LifeSpan Bioscience
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Polypeptide GalNac Transferase 4/GALNT4 Antibody - NBP1-62381 from Novus Biologicals
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Polypeptide GalNac Transferase 4/GALNT4 Antibody - NBP1-69399 from Novus Biologicals
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Polypeptide GalNac Transferase 4/GALNT4 Antibody - H00008693-B01 from Novus Biologicals
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Polypeptide GalNac Transferase 4/GALNT4 Antibody - H00008693-D01P from Novus Biologicals
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Anti-GALNT4 antibody produced in rabbit - SAB1411554 from Sigma-Aldrich
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Anti-GALNT4 (ab1) antibody produced in rabbit - SAB2100890 from Sigma-Aldrich
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GALNT4 antibody - middle region (ARP45527_P050) - ARP45527_P050 from Aviva Systems Biology
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GALNT4 antibody - C-terminal region (ARP45528_P050) - ARP45528_P050 from Aviva Systems Biology
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GALNT4 Antibody - N-terminal region (OAAB00196) - OAAB00196 from Aviva Systems Biology
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