Gene Symbol | GALNT4 |
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Entrez Gene | 8693 |
Alt Symbol | GALNAC-T4, GALNACT4 |
Species | Human |
Gene Type | protein-coding |
Description | polypeptide N-acetylgalactosaminyltransferase 4 |
Other Description | UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)|polypeptide GalNAc transferase 4|pp-GaNTase 4|protein-UDP acetylgalactosaminyltransferase 4 |
Swissprots | O00208 Q8N4A0 B4DMX6 B2R775 |
Accessions | CAA69875 EAW97428 Q8N4A0 AK026150 AK026438 AK312870 BAG35722 AW835269 BC036390 AAH36390 CR739813 DA109687 DQ891684 ABM82610 DQ894869 ABM85795 DQ896831 ABM87830 EU176606 ABW03407 NM_003774 NP_003765 |
Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a highest activity toward Muc7, EA2 and Muc2, with a lowest activity than GALNT2. Glycosylates 'Thr-57' of SELPLG. |
Subcellular Location | Golgi apparatus membrane {ECO:0000305|PubMed:9804815}; Single-pass type II membrane protein {ECO:0000305|PubMed:9804815}. |
Tissue Specificity | Ubiquitous. Highly expressed in mucous cells. {ECO:0000269|PubMed:9804815}. |
Top Pathways | Mucin type O-Glycan biosynthesis |
Human GALNT4 full length protein - ab160144 from Abcam
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GALNT4 Antibody Blocking Peptide - LS-E101 from LifeSpan Bioscience
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GALNT4 Antibody Blocking Peptide - LS-E16627 from LifeSpan Bioscience
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GALNT4 Antibody Blocking Peptide - LS-E16628 from LifeSpan Bioscience
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Recombinant Human Polypeptide GalNac Transferase 4/GALNT4 Protein - H00008693-P01 from Novus Biologicals
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GALNT4-Antibody-N-term-Blocking-peptide - BP10190a from Abgent, a WuXi AppTec company
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Recombinant Human GALNT4, CF - 7528-GT-020 from R&D Systems
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GALNT4 Blocking Peptide - 33R-1400 from Fitzgerald
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GALNT4 Blocking Peptide - 33R-9559 from Fitzgerald
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GALNT4 - H00008693-P01-10 from Acris Antibodies
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GALNT4 - H00008693-P01-25 from Acris Antibodies
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GALNT4 fusion protein - ag3590 from Proteintech Group
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Recombinant Human Polypeptide N-acetylgalactosaminyltransferase 4(GALNT4) - CSB-YP836662HU CSB-EP836662HU CSB-BP836662HU CSB-MP836662HU from Cusabio
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Recombinant Human GALNT4 Protein, CF - 7528-GT from R&D Systems
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GALNT4 Peptide, Human - M34GP06082H from Creative Peptides
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Polypeptide GalNac Transferase 4/GALNT4 Recombinant Protein Antigen - NBP2-55959PEP from Novus Biologicals
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Recombinant Human GALNT4 Protein, CF - 7528-GT from Novus Biologicals
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Recombinant Human GALNT4 Protein, GST-tagged - GALNT4-4703H from Creative Biomart
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