SPC25

Gene Symbol	SPC25
Entrez Gene	57405
Alt Symbol	AD024, SPBC25, hSpc25
Species	Human
Gene Type	protein-coding
Description	SPC25, NDC80 kinetochore complex component
Other Description	2600017H08Rik|SPC25, NDC80 kinetochore complex component, homolog|kinetochore protein Spc25|spindle pole body component 25 homolog
Swissprots	Q9HBM1 A8K4X8 D3DPC0
Accessions	AAY24098 EAX11288 EAX11289 EAX11290 Q9HBM1 AF225416 AAG09718 AK291093 BAF83782 AY456388 AAR88652 BC022255 AAH22255 CR457197 CAG33478 HQ447658 ADQ32143 XM_011511516 XP_011509818 XM_011546938 XP_011545240 XM_011546939 XP_011545241 XM_011546940 XP_011545242 NM_020675 NP_065726
Function	Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. {ECO:0000269|PubMed:14699129, ECO:0000269|PubMed:14738735}.
Subcellular Location	Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SPC25 full length protein - ab163545 from Abcam Category Protein Source Wheat germ Species Human

Human SPC25 peptide - ab23408 from Abcam Category Peptide

SPC25 Antibody Blocking Peptide - LS-E5066 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPC25 Antibody Blocking Peptide - LS-E22575 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SPC25 Protein - H00057405-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SPC25-Antibody-Center-Blocking-Peptide - BP17479c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPC25 Blocking Peptide - 33R-4299 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SPC25 / SPBC25 - H00057405-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Recombinant Human Kinetochore protein Spc25(SPC25) - CSB-YP881019HU CSB-EP881019HU CSB-BP881019HU CSB-MP881019HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SPC25 / SPBC25 (full length, N-term HIS tag) - TP760096 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

SPC25 Recombinant Protein Antigen - NBP2-47263PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SPC25 Protein - NBP2-47262PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SPC25 Peptide, Human - M34GP15014H from Creative Peptides Category Peptide Source Synthetic. Species Human

Kinetochore protein Spc25 (SPC25), Recombinant Protein - MBS1338601 from MyBioSource Category Protein Prices $975.00, $975.00, $1,200.00, $1,200.00, $1,470.00, $1,470.00, $1,935.00, $1,935.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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