SPC25

Gene Symbol SPC25
Entrez Gene 57405
Alt Symbol AD024, SPBC25, hSpc25
Species Human
Gene Type protein-coding
Description SPC25, NDC80 kinetochore complex component
Other Description 2600017H08Rik|SPC25, NDC80 kinetochore complex component, homolog|kinetochore protein Spc25|spindle pole body component 25 homolog
Swissprots Q9HBM1 A8K4X8 D3DPC0
Accessions AAY24098 EAX11288 EAX11289 EAX11290 Q9HBM1 AF225416 AAG09718 AK291093 BAF83782 AY456388 AAR88652 BC022255 AAH22255 CR457197 CAG33478 HQ447658 ADQ32143 XM_011511516 XP_011509818 XM_011546938 XP_011545240 XM_011546939 XP_011545241 XM_011546940 XP_011545242 NM_020675 NP_065726
Function Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. {ECO:0000269|PubMed:14699129, ECO:0000269|PubMed:14738735}.
Subcellular Location Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.

Spc25 CRISPR/Cas9 KO Plasmid (h) - sc-417956 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 HDR Plasmid (h) - sc-417956-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 Double Nickase Plasmid (h) - sc-417956-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 Double Nickase Plasmid (h2) - sc-417956-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 CRISPR Activation Plasmid (h) - sc-417956-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 CRISPR Activation Plasmid (h2) - sc-417956-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 Lentiviral Activation Particles (h) - sc-417956-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 Lentiviral Activation Particles (h2) - sc-417956-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Spc25 siRNA (h) - sc-76554 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Spc25 shRNA Plasmid (h) - sc-76554-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Spc25 shRNA (h) Lentiviral Particles - sc-76554-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU050161 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

MISSION® esiRNA - EHU055341 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20436 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20436 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SPC25 siRNA (Human) - CRJ1432 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPC25 - MBS8211400 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SPC25 (NM_020675.3) - SHH416300 from Creative biogene

Category siRNA
Species Reactivities Human

Human SPC25 siRNA - orb271933 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPC25 shRNA Plasmid (Human) - CHJ1432 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SPC25 miRNA 3'UTR clone - MiUTR1H-09826 from Creative biogene

Species Reactivities Human
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