GATM

Gene Symbol GATM
Entrez Gene 2628
Alt Symbol AGAT, AT, CCDS3
Species Human
Gene Type protein-coding
Description glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Other Description glycine amidinotransferase, mitochondrial|transamidinase
Swissprots B4DH99 Q53EQ4 B4DPI3 P50440
Accessions EAW77306 EAW77307 EAW77308 P50440 AK098055 AK098393 AK223585 BAD97305 AK294995 BAG58060 AK298350 BAG60595 BC004141 AAH04141 BC039389 CD365153 DB048816 DB457418 S68805 AAB29892 XM_011521450 XP_011519752 XM_011521451 XP_011519753 NM_001482 NP_001473
Function Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis. {ECO:0000269|PubMed:16125225, ECO:0000269|PubMed:16614068, ECO:0000269|PubMed:16820567}.
Subcellular Location Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane.
Tissue Specificity Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues. {ECO:0000269|PubMed:16125225, ECO:0000269|PubMed:16614068, ECO:0000269|PubMed:16820567}.
Top Pathways Glycine, serine and threonine metabolism, Arginine and proline metabolism

AGAT (T-16) - sc-241785 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AGAT (T-16): sc-241785. Western blot analysis of AGAT expression in human kidney (A) and mouse kidney (B) tissue extracts.

Anti-GATM antibody - ab87062 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GATM antibody (ab87062) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-GATM antibody - ab67713 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-GATM antibody (ab67713) at 1/500 dilution + human liver at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-GATM antibody - ab107500 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GATM antibody (ab107500) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-GATM antibody [1C9] - ab119269 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C9
All lanes : Anti-GATM antibody [1C9] (ab119269) at 1/500 dilutionLane 1 : HEK293T lysate transfected with pCMV6-ENTRY control cDNA for 48 hrs Lane 2 : HEK293T lysate transfected with pCMV6-ENTRY GATM cDNA for 48 hrs Lysates/proteins at 5 µg per lane.

Anti-GATM antibody - C-terminal - ab156265 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GATM antibody - C-terminal (ab156265) at 1/100 dilution + A549 cell line lysate at 35 µg

Anti-GATM / AGAT Antibody (aa350-378, AP) - LS-C214605 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa350-378, Biotin) - LS-C214607 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (clone 2H7) - LS-C197279 from LifeSpan Bioscience

Prices $355.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 2H7

Anti-GATM / AGAT Antibody (aa350-378, APC) - LS-C214606 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa350-378, FITC) - LS-C214609 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa350-378, Azide-free, HRP) - LS-C214610 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa58-84, AP) - LS-C214612 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa350-378, PE) - LS-C214611 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa58-84, APC) - LS-C214613 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa58-84, Biotin) - LS-C214614 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa58-84, FITC) - LS-C214616 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa58-84, Azide-free, HRP) - LS-C214615 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa58-84, PE) - LS-C214617 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody - LS-C308059 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa70-100) - LS-C321561 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa350-378) - LS-C321560 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GATM / AGAT Antibody (aa251-300) - LS-C102306 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
GATM antibody LS-C102306 Western blot of 721_B cell lysate.

Anti-GATM / AGAT Antibody (aa58-84) - LS-C166389 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GATM antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-GATM / AGAT Antibody - LS-C334819 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using GATM antibody.
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