GATM

Gene Symbol GATM
Entrez Gene 2628
Alt Symbol AGAT, AT, CCDS3
Species Human
Gene Type protein-coding
Description glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Other Description glycine amidinotransferase, mitochondrial|transamidinase
Swissprots B4DH99 Q53EQ4 B4DPI3 P50440
Accessions EAW77306 EAW77307 EAW77308 P50440 AK098055 AK098393 AK223585 BAD97305 AK294995 BAG58060 AK298350 BAG60595 BC004141 AAH04141 BC039389 CD365153 DB048816 DB457418 S68805 AAB29892 XM_011521450 XP_011519752 XM_011521451 XP_011519753 NM_001482 NP_001473
Function Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis. {ECO:0000269|PubMed:16125225, ECO:0000269|PubMed:16614068, ECO:0000269|PubMed:16820567}.
Subcellular Location Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane.
Tissue Specificity Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues. {ECO:0000269|PubMed:16125225, ECO:0000269|PubMed:16614068, ECO:0000269|PubMed:16820567}.
Top Pathways Glycine, serine and threonine metabolism, Arginine and proline metabolism

AGAT CRISPR/Cas9 KO Plasmid (h) - sc-405809 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT HDR Plasmid (h) - sc-405809-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT Double Nickase Plasmid (h) - sc-405809-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT Double Nickase Plasmid (h2) - sc-405809-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT CRISPR Activation Plasmid (h) - sc-405809-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT CRISPR Activation Plasmid (h2) - sc-405809-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT Lentiviral Activation Particles (h) - sc-405809-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT Lentiviral Activation Particles (h2) - sc-405809-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

AGAT siRNA (h) - sc-90190 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AGAT shRNA Plasmid (h) - sc-90190-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

AGAT shRNA (h) Lentiviral Particles - sc-90190-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU045661 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9156 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9156 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07661 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07661

GATM siRNA (Human) - CRH1744 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GATM - MBS8202437 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GATM(NM_001482.2) - SHH078527 from Creative biogene

Category siRNA
Species Reactivities Human

GATM shRNA Plasmid (Human) - CHH1744 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GATM miRNA 3'UTR clone - MiUTR1H-03969 from Creative biogene

Species Reactivities Human
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