PREB

Gene Symbol	PREB
Entrez Gene	10113
Alt Symbol	SEC12
Species	Human
Gene Type	protein-coding
Description	prolactin regulatory element binding
Other Description	mammalian guanine nucleotide exchange factor mSec12|prolactin regulatory binding-element protein|prolactin regulatory element-binding protein
Swissprots	Q53SZ8 Q9HCU5 Q9UH94
Accessions	AAF74572 AAX93170 EAX00626 EAX00627 EAX00628 EAX00629 EAX00630 Q9HCU5 AA629936 AF203687 AAF19192 AF226684 AAG01692 AK001976 AK023064 BAB14385 AK023405 AK292178 BAF84867 BC002765 AAH02765 BC008658 BC012890 AAH12890 BC016472 AAH16472 BC016906 AAH16906 BC036185 BC041032 AAH41032 BG715668 DQ892120 ABM83046 XM_006711914 XP_006711977 XM_011532471 XP_011530773 XM_011532472 XP_011530774 XR_939648 XR_939649 NM_013388 NP_037520
Function	Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10920239, ECO:0000269|PubMed:12735795}.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PREB full length protein - ab160825 from Abcam Category Protein Source Wheat germ Species Human

Human PREB protein fragment - ab160826 from Abcam Category Protein Source Wheat germ Species Human

PREB Antibody Blocking Peptide - LS-E12067 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PREB Antibody Blocking Peptide - LS-E21180 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PREB Protein - H00010113-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human PREB Protein - H00010113-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PREB Blocking Peptide - 33R-8243 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PREB - H00010113-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

PREB - H00010113-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PREB - H00010113-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PREB fusion protein - Ag0202 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human PREB, GST-tagged - PREB-1940H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Prolactin regulatory element-binding protein(PREB) - CSB-YP867205HU CSB-EP867205HU CSB-BP867205HU CSB-MP867205HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PREB - TP308351 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Prolactin regulatory element-binding protein (PREB), Recombinant Protein - MBS1304852 from MyBioSource Category Protein Prices $1,160.00, $1,160.00, $1,390.00, $1,390.00, $1,855.00, $1,855.00, $2,315.00, $2,315.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PREB Recombinant Protein Antigen - NBP1-87057PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PREB Recombinant Protein Antigen - NBP1-87056PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PREB Peptide, Human - M34GP12365H from Creative Peptides Category Peptide Source Synthetic. Species Human

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