PREB

Gene Symbol PREB
Entrez Gene 10113
Alt Symbol SEC12
Species Human
Gene Type protein-coding
Description prolactin regulatory element binding
Other Description mammalian guanine nucleotide exchange factor mSec12|prolactin regulatory binding-element protein|prolactin regulatory element-binding protein
Swissprots Q53SZ8 Q9HCU5 Q9UH94
Accessions AAF74572 AAX93170 EAX00626 EAX00627 EAX00628 EAX00629 EAX00630 Q9HCU5 AA629936 AF203687 AAF19192 AF226684 AAG01692 AK001976 AK023064 BAB14385 AK023405 AK292178 BAF84867 BC002765 AAH02765 BC008658 BC012890 AAH12890 BC016472 AAH16472 BC016906 AAH16906 BC036185 BC041032 AAH41032 BG715668 DQ892120 ABM83046 XM_006711914 XP_006711977 XM_011532471 XP_011530773 XM_011532472 XP_011530774 XR_939648 XR_939649 NM_013388 NP_037520
Function Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER. {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:10920239, ECO:0000269|PubMed:12735795}.
Top Pathways Protein processing in endoplasmic reticulum

PREB CRISPR/Cas9 KO Plasmid (h) - sc-411416 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB HDR Plasmid (h) - sc-411416-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB Double Nickase Plasmid (h) - sc-411416-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB Double Nickase Plasmid (h2) - sc-411416-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB CRISPR Activation Plasmid (h) - sc-411416-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB CRISPR Activation Plasmid (h2) - sc-411416-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB Lentiviral Activation Particles (h) - sc-411416-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB Lentiviral Activation Particles (h2) - sc-411416-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PREB siRNA (h) - sc-94852 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PREB shRNA Plasmid (h) - sc-94852-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PREB shRNA (h) Lentiviral Particles - sc-94852-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PREB RNAi - H00010113-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU050401 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17388 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17388 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05779 from Sigma-Aldrich

Category miRNA

PREB siRNA (Human) - CRH6819 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PREB (NM_013388.4) - SHH382372 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PREB(NM_013388.4) - SHR137992 from Creative biogene

Category siRNA
Species Reactivities Human

PREB shRNA Plasmid (Human) - CHH6819 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PREB miRNA 3'UTR clone - MiUTR1H-08239 from Creative biogene

Species Reactivities Human
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