ERLIN2

Gene Symbol	ERLIN2
Entrez Gene	11160
Alt Symbol	C8orf2, Erlin-2, NET32, SPFH2, SPG18
Species	Human
Gene Type	protein-coding
Description	ER lipid raft associated 2
Other Description	SPFH domain family, member 2|endoplasmic reticulum lipid raft-associated protein 2|erlin-2|stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
Swissprots	O94905 A8K5S9 D3DSW0 B4DM38 Q86VS6 Q6NW21 Q86W49 A0JLQ1
Accessions	BAA36845 EAW63365 EAW63366 O94905 AK057557 AK291394 BAF84083 AK297279 BAG59750 AL442077 CAC09443 AY358108 AAQ88475 AY358851 AAQ89210 BC005950 AAH05950 BC035980 BC048308 AAH48308 BC050611 AAH50611 BC067765 AAH67765 BI560439 BP353279 BP363612 BU608317 XM_005273392 XP_005273449 XM_006716280 XP_006716343 NM_001003790 NP_001003790 NM_001003791 NP_001003791 NM_007175 NP_009106
Function	Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway. {ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}; Single-pass type II membrane protein {ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:10449903}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SPFH2 full length protein - ab132416 from Abcam Category Protein Source Wheat germ Species Human

Human SPFH2 protein fragment - ab136707 from Abcam Category Protein Source E. coli Species Human

SPFH2 peptide (328-339 ) - ab45803 from Abcam Category Peptide Species Human

SPFH2 / ERLIN2 Antibody Blocking Peptide - LS-E5976 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPFH2 / ERLIN2 Antibody Blocking Peptide - LS-E21384 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SPFH2 / ERLIN2 Antibody Blocking Peptide - LS-E25934 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SPFH2 Protein - H00011160-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human SPFH2 Protein - NBP2-23027 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

ERLIN2-Antibody-C-term-Blocking-Peptide - BP18538b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SPFH2 blocking peptide - GTX89522-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Rat

Human ERLIN2 protein - orb168312 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli

ERLIN2 Blocking Peptide - 33R-1518 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ERLIN2 protein (His tag) - 80R-2560 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

SPFH2 Peptide - AC21-0763-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Erlin-2 (25-339, His-tag) - AR50606PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Erlin-2 (25-339, His-tag) - AR50606PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Erlin-2 - H00011160-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Erlin-2 - H00011160-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ERLIN2, 25-339aa, Human, His tag, E.coli - 01-P1782 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

ERLIN2 Peptide - 45-552P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

ERLIN2 fusion protein - ag6250 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ERLIN2 fusion protein - Ag6369 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

ERLIN2 Human - PRPS-1273 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human ER lipid raft associated 2, His-tagged - ERLIN2-343H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Endoplasmic Reticulum Lipid Raft Associated Protein 2 (ERLIN2) - RPL504Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

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