ERLIN2

Gene Symbol ERLIN2
Entrez Gene 11160
Alt Symbol C8orf2, Erlin-2, NET32, SPFH2, SPG18
Species Human
Gene Type protein-coding
Description ER lipid raft associated 2
Other Description SPFH domain family, member 2|endoplasmic reticulum lipid raft-associated protein 2|erlin-2|stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2
Swissprots O94905 A8K5S9 D3DSW0 B4DM38 Q86VS6 Q6NW21 Q86W49 A0JLQ1
Accessions BAA36845 EAW63365 EAW63366 O94905 AK057557 AK291394 BAF84083 AK297279 BAG59750 AL442077 CAC09443 AY358108 AAQ88475 AY358851 AAQ89210 BC005950 AAH05950 BC035980 BC048308 AAH48308 BC050611 AAH50611 BC067765 AAH67765 BI560439 BP353279 BP363612 BU608317 XM_005273392 XP_005273449 XM_006716280 XP_006716343 NM_001003790 NP_001003790 NM_001003791 NP_001003791 NM_007175 NP_009106
Function Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Also involved in ITPR1 degradation by the ERAD pathway. {ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}; Single-pass type II membrane protein {ECO:0000269|PubMed:16835267, ECO:0000269|PubMed:17502376, ECO:0000269|PubMed:19240031}. Note=Associated with lipid raft-like domains of the endoplasmic reticulum membrane.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:10449903}.

SPFH2 CRISPR/Cas9 KO Plasmid (h) - sc-404527 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 HDR Plasmid (h) - sc-404527-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 Double Nickase Plasmid (h) - sc-404527-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 Double Nickase Plasmid (h2) - sc-404527-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 CRISPR Activation Plasmid (h) - sc-404527-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 CRISPR Activation Plasmid (h2) - sc-404527-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 Lentiviral Activation Particles (h) - sc-404527-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 Lentiviral Activation Particles (h2) - sc-404527-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPFH2 siRNA (h) - sc-76559 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPFH2 shRNA Plasmid (h) - sc-76559-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPFH2 shRNA (h) Lentiviral Particles - sc-76559-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU123761 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7969 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7969 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ERLIN2 siRNA (Human) - CRH7641 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ERLIN2 - MBS8214190 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ERLIN2 (NM_007175.6) - SHH287133 from Creative biogene

Category siRNA
Species Reactivities Human

ERLIN2 shRNA Plasmid (Human) - CHH7641 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ERLIN2 miRNA 3'UTR clone - MiUTR1H-03300 from Creative biogene

Species Reactivities Human

ERLIN2 miRNA 3'UTR clone - MiUTR3H-12004 from Creative biogene

Species Reactivities Human

ERLIN2 miRNA 3'UTR clone - MiUTR3H-12005 from Creative biogene

Species Reactivities Human
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