CBX4

Gene Symbol	CBX4
Entrez Gene	8535
Alt Symbol	NBP16, PC2
Species	Human
Gene Type	protein-coding
Description	chromobox homolog 4
Other Description	E3 SUMO-protein ligase CBX4|NS5ATP1-binding protein 16|Pc class 2 homolog|chromobox homolog 4 (Pc class homolog, Drosophila)|chromobox protein homolog 4|polycomb 2 homolog
Swissprots	Q96C04 Q6TPI8 B1PJR7 O00257
Accessions	EAW89572 EAW89573 O00257 AF013956 AAB80718 AI796748 AY390430 AAQ97596 BC014967 AAH14967 BG029608 BQ225831 EU439707 ACA49234 U94344 AAB62734 XM_011525399 XP_011523701 NM_003655 NP_003646
Function	E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131.
Subcellular Location	Nucleus. Nucleus speckle. Note=Localization to nuclear polycomb bodies is required for ZNF131 sumoylation.
Tissue Specificity	Ubiquitous.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CBX4 full length protein - ab152885 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Recombinant Human CBX4 Protein - H00008535-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

CBX4 Peptide - P1125 from Novus Biologicals Category Peptide Species Human

CBX4 Peptide - P1124 from Novus Biologicals Category Peptide Species Human

CBX4-Antibody-N-term-Blocking-Peptide - BP17028a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CBX4-Antibody-C-term-Blocking-Peptide - BP2514b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PC2-CBX4-Antibody-N-term-Blocking-peptide - BP2514a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CBX4 / PC2 - H00008535-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

CBX4 / PC2 (N-term) Control Peptide - AP55488CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CBX4 Peptide - 7007P from ProSci Category Peptide Species Human

CBX4 fusion protein - Ag13425 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CBX4 fusion protein - ag13450 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human CBX4, GST-tagged - CBX4-10769H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human E3 SUMO-protein ligase CBX4(CBX4) - CSB-YP004600HU CSB-EP004600HU CSB-BP004600HU CSB-MP004600HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CBX4 Recombinant Protein Antigen - NBP1-83225PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CBX4 Peptide, Human - M34GP02439H from Creative Peptides Category Peptide Source Synthetic. Species Human

CBX4 Recombinant Protein Antigen - NBP2-55246PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

E3 SUMO-protein ligase CBX4 (CBX4), Recombinant Protein - MBS1034074 from MyBioSource Category Protein Prices $1,355.00, $1,355.00, $1,575.00, $1,575.00, $2,250.00, $2,250.00, $2,715.00, $2,715.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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