DCLRE1B

Gene Symbol DCLRE1B
Entrez Gene 64858
Alt Symbol APOLLO, SNM1B, SNMIB
Species Human
Gene Type protein-coding
Description DNA cross-link repair 1B
Other Description 5' exonuclease Apollo|DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)|PSO2 homolog|SNM1 homolog B
Swissprots Q9H816 Q9H9E5
Accessions AAV97812 EAW56582 EAW56583 Q9H816 AF306690 AF306691 AF306692 AF306693 AI669133 AK022872 BAB14284 AK024060 BAB14807 BC011950 BC029687 AAH29687 CR936679 DR005221 JF432466 ADZ15683 XM_005271130 XP_005271187 NM_022836 NP_073747
Function 5'-3' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)- mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity: generates 3' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are vulnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage: plays a
Subcellular Location Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.

SNM1B (B-7) - sc-514300 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNM1B (B-7): sc-514300. Western blot analysis of SNM1B expression in non-transfected: sc-117752 (A) and human SNM1B transfected: sc-113949 (B) 293T whole cell lysates.

SNM1B (F-8) - sc-374351 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SNM1B (F-8): sc-374351. Western blot analysis of SNM1B expression in non-transfected: sc-117752 (A) and human SNM1B transfected: sc-113949 (B) 293T whole cell lysates.

SNM1B (H-96) - sc-368042 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
SNM1B (H-96): sc-368042. Western blot analysis of SNM1B expression in mouse testis tissue extract.

SNM1B (P-14) - sc-135523 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
SNM1B (P-14): sc-135523. Western blot analysis of SNM1B expression in non-transfected: sc-117752 (A) and human SNM1B transfected: sc-113949 (B) 293T whole cell lysates.

SNM1B (N-12) - sc-135522 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa208-236) - LS-C167295 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
DCLRE1B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human prostate carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-DCLRE1B Antibody (aa1-280, clone 2B7) - LS-C337240 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B7
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-DCLRE1B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-DCLRE1B Antibody (aa513-530) - LS-C144186 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa208-236, APC) - LS-C234455 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa208-236, AP) - LS-C234456 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa513-530) - LS-C148948 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa208-236, Biotin) - LS-C234457 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa208-236, PE) - LS-C234462 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa208-236, FITC) - LS-C234458 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa208-236, Azide-free, HRP) - LS-C249803 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCLRE1B Antibody (aa215-244) - LS-C320763 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

DCLRE1B Antibody (2B7) - NBP2-03563 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B7
Western Blot: DCLRE1B Antibody (2B7) [NBP2-03563] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DCLRE1B (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DCLRE1B.

ANTI-DCLRE1B (CENTER) antibody produced in rabbit - SAB1301487 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>DCLRE1B (Center): <B>Cat. No. SAB1301487</B>: DCLRE1B in Human prostate carcinoma tissue with DCLRE1B antibody (Center) at 5 μg/mL.

DCLRE1B Antibody - middle region (OAAB02841) - OAAB02841 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

DCLRE1B-Antibody-Center - AP5426c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
DCLRE1B Antibody (Center)(Cat. #AP5426c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the DCLRE1B antibody detected DCLRE1B protein (arrow).

DCLRE1B antibody [N1C1] - GTX116777 from GeneTex

Host Rabbit
Clonality Polyclonal

DCLRE1B antibody - orb35722 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed and paraffin embedded human prostate carcinoma tissue using DCLRE1B antibody
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