CYP4A11

Gene Symbol CYP4A11
Entrez Gene 1579
Alt Symbol CP4Y, CYP4A2, CYP4AII
Species Human
Gene Type protein-coding
Description cytochrome P450, family 4, subfamily A, polypeptide 11
Other Description 20-HETE synthase|20-hydroxyeicosatetraenoic acid synthase|CYPIVA11|P450HL-omega|alkane-1 monooxygenase|cytochrome P-450HK-omega|cytochrome P450 4A11|cytochrome P450, subfamily IVA, polypeptide 11|cytochrome P450HL-omega|fatty acid omega-hydroxylase|lauric acid omega-hydroxylase
Swissprots Q06766 Q8IWY5 Q16865 Q5VSP8 Q02928 Q86SU6 Q16866
Accessions AAO16078 AAQ56847 Q02928 AK298267 BAG60530 AK298413 BAG60640 BC022851 BC041158 AAH41158 CD014132 D13705 BAA02864 D26481 BAA05491 L04751 AAA58436 S67580 AAB29502 S67581 AAB29503 X71480 CAA50586 XM_005270539 XP_005270596 XM_011540826 XP_011539128 XM_011540827 XP_011539129 XM_011540828 XP_011539130 XM_011540829 XP_011539131 XM_011540830 XP_011539132 XR_246241 XR_246242 NM_000778 NP_000769
Function Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE). {ECO:0000269|PubMed:15611369, ECO:0000269|PubMed:1739747, ECO:0000269|PubMed:7679927}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Kidney and liver. {ECO:0000269|PubMed:7679927}.
Top Pathways Vascular smooth muscle contraction, Arachidonic acid metabolism, Fatty acid degradation, Retinol metabolism

Human Cytochrome P450 4A11/22 full length protein - ab114572 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE Stained with Coomassie Blue

CYP4A11 Antibody Blocking Peptide - LS-E9345 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Cytochrome P450 4A Protein - H00001579-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CYP4A11-4A22-Antibody-C-term-Blocking-Peptide - BP7884b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Cytochrome P450 4A11/22 Blocking Peptide - abx062517 from Abbexa

Category Peptide
Species Human

CYP4A11 - H00001579-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CYP4A11 - H00001579-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CYP4A11 fusion protein - Ag2300 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human CYP4A11 - CYP4A11-26692TH from Creative Biomart

Category Protein
Source Wheat germ

Recombinant Human CYP4A11, GST-tagged - CYP4A11-11787H from Creative Biomart

Category Protein
Source E.coli
Species Human

Cytochrome P450 4A11/22 Blocking Peptide - CBP1323 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human

CYP4A11 Peptide - abx165242 from Abbexa

Category Peptide
Species Human, Mouse, Rat

CYP4A11 Protein - abx163697 from Abbexa

Category Protein
Species Human

CYP4A11-Antibody-N-term-Blocking-Peptide - BP7884a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CYP4A11 Peptide, Human - M34GP03975H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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