TAB3

Gene Symbol TAB3
Entrez Gene 257397
Alt Symbol MAP3K7IP3, NAP1
Species Human
Gene Type protein-coding
Description TGF-beta activated kinase 1/MAP3K7 binding protein 3
Other Description NF-kappa-B-activating protein 1|NFkB activating protein 1|TAB-3|TAK1-binding protein 3|TGF-beta-activated kinase 1 and MAP3K7-binding protein 3|TGF-beta-activated kinase 1-binding protein 3|mitogen-activated protein kinase kinase kinase 7 interacting protein 3
Swissprots Q6VQR0 A6NDD9 Q8N5C8
Accessions EAW99057 EAW99058 EAW99059 Q8N5C8 AK096786 AK297274 BAG59746 AL832071 CAI46137 AY331591 AAQ92938 AY331592 AAQ92939 AY371491 AAQ88279 AY437560 AAR06179 BC032526 AAH32526 BU849692 DA494641 XM_005274482 XP_005274539 XM_005274483 XP_005274540 XM_005274484 XP_005274541 XM_011545487 XP_011543789 XM_011545488 XP_011543790 XR_430492 XR_950433 XR_950434 XR_950435 NM_152787 NP_690000 NM_198312
Function Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor. {ECO:0000269|PubMed:14633987, ECO:0000269|PubMed:14766965}.
Tissue Specificity Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript. {ECO:0000269|PubMed:14670075, ECO:0000269|PubMed:14766965}.
Top Pathways NOD-like receptor signaling pathway, TNF signaling pathway

TAB3 (D5J7D) Rabbit mAb - 14241 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D5J7D
Western blot analysis of extracts from 293T cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568, SignalSilence ® TAB3 siRNA I #14212, or SignalSilence ® TAB3 siRNA II #14225, using TAB3 (D5J7D) Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). The TAB3 (D5J7D) Rabbit mAb confirms silencing of TAB3 expression, while the β-Actin (D6A8) Rabbit mAb is used as a loading control.

TAB3 (D-9) - sc-166538 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TAB3 (D-9): sc-166538. Western blot analysis of TAB3 expression in Hep G2 whole cell lysate.

TAB3 (D-12) - sc-46547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TAB3 (H-128) - sc-67112 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TAB3 (H-128): sc-67112. Western blot analysis of TAB3 expression in c4 whole cell lysate.

TAB3 (T-14) - sc-46550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TAB3 antibody - ab85655 from Abcam

Prices $401.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TAB3 antibody (ab85655) at 0.4 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgLane 5 : NIH3T3 whole cell lysate at 50 µg

Anti-TAB3 antibody - ab79289 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab79289 at 1/50 dilution staining TAB3 in human brain by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.

Anti-TAB3 antibody - ab134806 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded (IHC-P) Human Thyroid tissue labelling TAB3 with ab134806 at 3.75 µg/ml.

Anti-TAB3 antibody - ab130370 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TAB3 antibody (ab130370) at 1/100 dilution + HL60 cell line lysates at 35 µg

Anti-TAB3 antibody [EPR5965] - ab124723 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5965
All lanes : Anti-TAB3 antibody [EPR5965] (ab124723) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : HepG2 cell lysateLane 3 : HeLa cell lysateLane 4 : Caco-2 cell lysateLane 5 : RAW264.7 cell lysateLane 6 : NIH 3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-TAB3 antibody - C-terminal - ab200148 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-TAB3 antibody - C-terminal (ab200148) at 1/1000 dilutionLane 1 : Mouse thymus total cell extractLane 2 : HeLa total cell extractLane 3 : Jurkat total cell extract

Anti-NAP1 / TAB3 Antibody (N-Terminus) IHC-plus™ - LS-B4705 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-TAB3 / MAP3K7IP3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4705 concentration 5 ug/ml.

Anti-NAP1 / TAB3 Antibody (aa59-69) IHC-plus™ - LS-B7358 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TAB3 / MAP3K7IP3 antibody IHC of human thyroid. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7358 concentration 3.75 ug/ml.

Anti-NAP1 / TAB3 Antibody (aa274-285) - LS-C55088 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody - LS-C153239 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa1-30, AP) - LS-C237380 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa50-100) - LS-C47297 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of TAB3 in human kidney lysate in the 1) absence and 2) presence of immunizing peptide using antibody at 0.5 ug/ml.

Anti-NAP1 / TAB3 Antibody (aa1-30, APC) - LS-C246482 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa1-30, FITC) - LS-C246483 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa1-30, Biotin) - LS-C246484 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa1-30, PE) - LS-C246485 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa650-700) - LS-C288962 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa1-30, Azide-free, HRP) - LS-C248761 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa600-650) - LS-C288961 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NAP1 / TAB3 Antibody (aa1-30) - LS-C322835 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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