TAB3

Gene Symbol	TAB3
Entrez Gene	257397
Alt Symbol	MAP3K7IP3, NAP1
Species	Human
Gene Type	protein-coding
Description	TGF-beta activated kinase 1/MAP3K7 binding protein 3
Other Description	NF-kappa-B-activating protein 1|NFkB activating protein 1|TAB-3|TAK1-binding protein 3|TGF-beta-activated kinase 1 and MAP3K7-binding protein 3|TGF-beta-activated kinase 1-binding protein 3|mitogen-activated protein kinase kinase kinase 7 interacting protein 3
Swissprots	Q6VQR0 A6NDD9 Q8N5C8
Accessions	EAW99057 EAW99058 EAW99059 Q8N5C8 AK096786 AK297274 BAG59746 AL832071 CAI46137 AY331591 AAQ92938 AY331592 AAQ92939 AY371491 AAQ88279 AY437560 AAR06179 BC032526 AAH32526 BU849692 DA494641 XM_005274482 XP_005274539 XM_005274483 XP_005274540 XM_005274484 XP_005274541 XM_011545487 XP_011543789 XM_011545488 XP_011543790 XR_430492 XR_950433 XR_950434 XR_950435 NM_152787 NP_690000 NM_198312
Function	Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor. Isoform 2 may be an oncogenic factor. {ECO:0000269|PubMed:14633987, ECO:0000269|PubMed:14766965}.
Tissue Specificity	Widely expressed. Constitutively overexpressed in certain tumor tissues. Isoform 1 is a major transcript while isoform 2 is a minor transcript. {ECO:0000269|PubMed:14670075, ECO:0000269|PubMed:14766965}.
Top Pathways	NOD-like receptor signaling pathway, TNF signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TAB3 full length protein - ab166083 from Abcam Category Protein Source Wheat germ Species Human

Human TAB3 protein fragment - ab153638 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human NAP1 Protein - H00257397-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human NAP1 Protein - H00257397-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

MAP3K7IP3-Antibody-N-term-Blocking-Peptide - BP17071a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TAB3 Peptide - AC21-1324-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TAB3 Peptide - AC21-1333-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

TAB3 / MAP3K7IP3 - H00257397-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

TAB3 / MAP3K7IP3 - H00257397-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TAB3 / MAP3K7IP3 - H00257397-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TAB3 / MAP3K7IP3 (N-term) Control Peptide - AP55458CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

MAP3K7IP3 Peptide - 45-863P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

MAP3K7IP3 Peptide - 45-864P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

TAB3 Peptide - 3391P from ProSci Category Peptide Species Human

MAP3K7IP3 fusion protein - Ag4699 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human MAP3K7IP3, His-tagged - MAP3K7IP3-737H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human TGF-beta-activated kinase 1 and MAP3K7-binding protein 3(TAB3) - CSB-YP850806HU CSB-EP850806HU CSB-BP850806HU CSB-MP850806HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (TAB3), Recombinant Protein - MBS1375003 from MyBioSource Category Protein Prices $1,520.00, $1,520.00, $1,745.00, $1,745.00, $2,600.00, $2,600.00, $3,045.00, $3,045.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

MAP3K7IP3, Peptide - MBS426497 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

MAP3K7IP3, Peptide - MBS428027 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

NAP1 Recombinant Protein Antigen - NBP1-81262PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NAP1 Recombinant Protein Antigen - NBP2-33985PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TAB3 Peptide, Human - M34GP15525H from Creative Peptides Category Peptide Source Synthetic. Species Human

MAP3K7IP3 Immunizing peptide - orb17486 from Biorbyt Category Peptide

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