Nr1h4

Gene Symbol Nr1h4
Entrez Gene 20186
Alt Symbol AI957360, Fxr, HRR1, RIP14, Rxrip14
Species Mouse
Gene Type protein-coding
Description nuclear receptor subfamily 1, group H, member 4
Other Description RXR-interacting protein 14|bile acid receptor|farnesoid X activated receptor|farnesoid X-activated receptor|farnesol receptor HRR-1|retinoid X receptor-interacting protein 14
Swissprots Q60642 Q60643 E9QJW2 Q60641
Accessions AAK15460 AAQ73843 AAQ73844 EDL21500 EDL21501 EDL21502 Q60641 AK002513 AK050566 AK132255 BAE21061 BC015261 AAH15261 U09416 AAC53066 U09417 AAC53065 U09418 AAC52978 XM_006513391 XP_006513454 XM_006513393 XP_006513456 NM_001163504 NP_001156976 NM_001163700 NP_001157172 NM_009108 NP_033134
Function Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Expressed specifically in liver and kidney.
Top Pathways Bile secretion

FXR/NR1H4 Antibody - NB400-153 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: FXR Antibody [NB400-153] - Detection of FXR in HeLa nuclear extract using NB400-153. ECL 30 minute detection.

FXR/NR1H4 Antibody [DyLight 405] - NB400-153V from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [FITC] - NB400-153F from Novus Biologicals

Prices $309.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [Alexa Fluor (R) 488] - NB400-153AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [Alexa Fluor (R) 405] - NB400-153AF405 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [Alexa Fluor (R) 700] - NB400-153AF700 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [Alexa Fluor (R) 647] - NB400-153AF647 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [DyLight 550] - NB400-153R from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [DyLight 488] - NB400-153G from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [HRP] - NB400-153H from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [DyLight 650] - NB400-153C from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

FXR/NR1H4 Antibody [Biotin] - NB400-153B from Novus Biologicals

Prices $309.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NR1H4 antibody - GTX82864 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-FXR antibody used in Western blot. GTX82864

Anti-NR1H4 (aa 224-238) polyclonal antibody - DPABH-27897 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

FXR Polyclonal Antibody - PA1-334 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot detection of FXR from 50 ug of mouse liver extract. Lane 1 is incubated with PA1-334 (1:500), and lane 2 has the antibody plus the neutralizing peptide (PEP-273).

Polyclonal Antibody to Farnesoid X Receptor (FXR) - PAC042Mu01 from Cloud-clone

Host Rabbit
Clonality Polyclonal

Polyclonal Antibody to Farnesoid X Receptor (FXR) - PAC042Mu02 from Cloud-clone

Host Rabbit
Clonality Polyclonal
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