Nr1h4

Gene Symbol	Nr1h4
Entrez Gene	20186
Alt Symbol	AI957360, Fxr, HRR1, RIP14, Rxrip14
Species	Mouse
Gene Type	protein-coding
Description	nuclear receptor subfamily 1, group H, member 4
Other Description	RXR-interacting protein 14|bile acid receptor|farnesoid X activated receptor|farnesoid X-activated receptor|farnesol receptor HRR-1|retinoid X receptor-interacting protein 14
Swissprots	Q60642 Q60643 E9QJW2 Q60641
Accessions	AAK15460 AAQ73843 AAQ73844 EDL21500 EDL21501 EDL21502 Q60641 AK002513 AK050566 AK132255 BAE21061 BC015261 AAH15261 U09416 AAC53066 U09417 AAC53065 U09418 AAC52978 XM_006513391 XP_006513454 XM_006513393 XP_006513456 NM_001163504 NP_001156976 NM_001163700 NP_001157172 NM_009108 NP_033134
Function	Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) and activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 within its gene locus (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000305}.
Tissue Specificity	Expressed specifically in liver and kidney.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones

Recombinant Farnesoid X Receptor (FXR) - RPC042Mu01 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Farnesoid X Receptor (FXR) - RPC042Mu02 from Cloud-clone Category Protein Source E.coli Species Mouse

Recombinant Mouse Bile acid receptor(Nr1h4) - CSB-YP723332MO CSB-EP723332MO CSB-BP723332MO CSB-MP723332MO from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Mouse

Bile acid receptor (Nr1h4), Recombinant Protein - MBS1398708 from MyBioSource Category Protein Prices $1,275.00, $1,275.00, $1,495.00, $1,495.00, $2,085.00, $2,085.00, $2,550.00, $2,550.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Mouse

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