DPPA3

Gene Symbol DPPA3
Entrez Gene 359787
Alt Symbol STELLA
Species Human
Gene Type protein-coding
Description developmental pluripotency associated 3
Other Description developmental pluripotency-associated protein 3|stella-related protein
Swissprots Q0P5U3 Q6JZS6 Q6W0C5
Accessions EAW88657 EAW88658 Q6W0C5 AY317075 AAQ84110 BC160067 AAI60067 NM_199286 NP_954980
Function Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. A
Subcellular Location Nucleus {ECO:0000269|PubMed:21421998}. Cytoplasm {ECO:0000269|PubMed:21421998}. Note=Mainly localizes in the female pronucleus, localization to the male pronucleus in much weaker. {ECO:0000250}.
Tissue Specificity Low expression in testis, ovary and thymus. Expressed in embryonic stem and carcinoma cells. Highly expressed in testicular germ cell tumors. {ECO:0000269|PubMed:14654002, ECO:0000269|PubMed:14684992, ECO:0000269|PubMed:14990856}.

STELLA (D-5) - sc-376862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
STELLA (D-5): sc-376862. Western blot analysis of STELLA expression in FHs 173We whole cell lysate.

STELLA (FL-159) - sc-67250 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
STELLA (FL-159): sc-67250. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ovary tissue showing nuclear and cytoplasmic staining of follicle cells and ovarian stroma cells.

STELLA (N-20) - sc-51435 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Stella antibody - ab74531 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-Stella antibody (ab74531) at 1 µg/mlLane 2 : Anti-Stella antibody (ab74531) at 2 µg/mlLane 1 : 293 cell lysateLane 2 : 293 cell lysateLysates/proteins at 15 µg per lane.

Anti-Stella antibody - ab169424 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Stella antibody (ab169424) at 1 µg/mlLane 1 : Stella transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-DPPA3 / STELLA Antibody (aa116-128) - LS-C55536 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-DPPA3 / STELLA Antibody (aa100-150) - LS-C148711 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of STELLAR in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top) and LS-C148711 (bottom) at 5 ug/ml.

Anti-DPPA3 / STELLA Antibody (N-Terminus) - LS-C345565 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of DPPA3 Antibody with human Breast Tumor lysate.

Anti-DPPA3 / STELLA Antibody (C-Terminus) - LS-C83905 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot of Stella in 293 cell lysate with Stella antibody at (A) 1 and (B) 2 ug/ml.

Anti-DPPA3 / STELLA Antibody (aa134-170) - LS-C344662 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysates from mouse liver, mouse testis tissue (from left to right) with (Mouse) Dppa3 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.

STELLAR Antibody - NBP2-27292 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: STELLAR Antibody [NBP2-27292] - Analysis of STELLAR in formalin-fixed, paraffin-embedded human brain tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml.

DPPA3 Antibody - NBP2-33448 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: DPPA3 Antibody [NBP2-33448] - prostate

Stella/Dppa3 Antibody - H00359787-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Stella/Dppa3 Antibody - NBP2-41089 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Stella/Dppa3 Antibody [NBP2-41089] - Western blot analysis of Stella in 293 cell lysate with Stella antibody at (A) 1 and (B) 2 ug/mL.

Stella/DPPA3 Polyclonal Antibody - bs-12280R from Bioss

Prices $279.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Stella/DPPA3 Polyclonal Antibody, Unconjugated (bs-12280R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12280R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12280R-A488 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12280R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12280R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, Cy3 Conjugated - bs-12280R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, Cy5 Conjugated - bs-12280R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, Cy5.5 Conjugated - bs-12280R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, Cy7 Conjugated - bs-12280R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, FITC Conjugated - bs-12280R-FITC from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Stella/DPPA3 Polyclonal Antibody, Biotin Conjugated - bs-12280R-Biotin from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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