TRA2B

Gene Symbol	TRA2B
Entrez Gene	6434
Alt Symbol	Htra2-beta, PPP1R156, SFRS10, SRFS10, TRA2-BETA, TRAN2B
Species	Human
Gene Type	protein-coding
Description	transformer 2 beta homolog (Drosophila)
Other Description	TRA-2 beta|protein phosphatase 1, regulatory subunit 156|splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)|transformer-2 protein homolog B|transformer-2 protein homolog beta
Swissprots	D3DNU3 B4DVK2 P62995
Accessions	AAD19277 AAD19278 AAD19279 EAW78204 EAW78205 EAW78206 EAW78207 EAW78208 P62995 AB209208 BAD92445 AK091863 AK094495 AK098191 BAC05256 AK125610 AK301118 BAG62714 AK308267 AK315632 BAG38000 BC000160 AAH00160 BC000451 AAH00451 BC005898 AAH05898 CR749214 CAH18071 DA164444 DQ890937 ABM81863 EU176532 ABW03333 U61267 AAC28242 U68063 AAB08701 U87836 AAB69763 XM_005247703 XP_005247760 XM_006713724 XP_006713787 XM_011513072 XP_011511374 NM_001243879 NP_001230808 NM_004593 NP_004584
Function	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre- mRNA. {ECO:0000269|PubMed:12165565, ECO:0000269|PubMed:12761049, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:9546399}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:9212162, ECO:0000269|PubMed:9546399}.
Tissue Specificity	Highest expression in heart, skeletal muscle and pancreas. Less abundant in kidney, placenta and brain. Lowest expression in kidney and liver. {ECO:0000269|PubMed:9790768}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TRA2B peptide - ab32689 from Abcam Category Peptide

Human TRA2B protein fragment - ab114393 from Abcam Category Protein Source E. coli Species Human

TRA2B / SFRS10 Antibody Blocking Peptide - LS-E3501 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRA2B / SFRS10 Antibody Blocking Peptide - LS-E14807 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human TRA2B Protein - H00006434-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TRA2B Recombinant Protein - H00006434-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

TRA2B-Antibody-Center-Blocking-Peptide - BP14688c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SFRS10 Blocking Peptide - 33R-6412 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SFRS10 Blocking Peptide - 33R-3636 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Transformer 2 Beta Protein - abx069418 from Abbexa Category Protein Source E.coli Species Human

TRA2B / SFRS10 - H00006434-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

TRA2B / SFRS10 - H00006434-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TRA2B / SFRS10 - H00006434-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Transformer 2 Beta (TRA2b), Human - 20-9527 from ARP American Research Products Category Protein Prices $569.00 Sizes 50 µg Source E.coli Species Human

TRA2B fusion protein - ag6993 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

TRA2B fusion protein - ag20683 from Proteintech Group Category Protein Source E. coli-derived, PET30a Species Human

TRA2B fusion protein - ag3937 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Transformer 2 Beta (TRA2b) - RPM389Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Transformer 2 Beta (TRA2b) - RPM389Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Transformer-2 protein homolog beta(TRA2B) - CSB-YP021143HU CSB-EP021143HU CSB-BP021143HU CSB-MP021143HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TRA2B / SFRS10 - TP301542 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

TRA2B Recombinant Protein Antigen - NBP2-49399PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

TRA2B Peptide, Human - M34GP16508H from Creative Peptides Category Peptide Source Synthetic. Species Human

TRA2B Recombinant Protein (OPCD07692) - OPCD07692 from Aviva Systems Biology Category Protein Source E.coli Species Human

TRA2B Recombinant Protein Antigen - NBP2-57661PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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