TRA2B

Gene Symbol	TRA2B
Entrez Gene	6434
Alt Symbol	Htra2-beta, PPP1R156, SFRS10, SRFS10, TRA2-BETA, TRAN2B
Species	Human
Gene Type	protein-coding
Description	transformer 2 beta homolog (Drosophila)
Other Description	TRA-2 beta|protein phosphatase 1, regulatory subunit 156|splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila)|transformer-2 protein homolog B|transformer-2 protein homolog beta
Swissprots	D3DNU3 B4DVK2 P62995
Accessions	AAD19277 AAD19278 AAD19279 EAW78204 EAW78205 EAW78206 EAW78207 EAW78208 P62995 AB209208 BAD92445 AK091863 AK094495 AK098191 BAC05256 AK125610 AK301118 BAG62714 AK308267 AK315632 BAG38000 BC000160 AAH00160 BC000451 AAH00451 BC005898 AAH05898 CR749214 CAH18071 DA164444 DQ890937 ABM81863 EU176532 ABW03333 U61267 AAC28242 U68063 AAB08701 U87836 AAB69763 XM_005247703 XP_005247760 XM_006713724 XP_006713787 XM_011513072 XP_011511374 NM_001243879 NP_001230808 NM_004593 NP_004584
Function	Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre- mRNA. {ECO:0000269|PubMed:12165565, ECO:0000269|PubMed:12761049, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:9546399}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:9212162, ECO:0000269|PubMed:9546399}.
Tissue Specificity	Highest expression in heart, skeletal muscle and pancreas. Less abundant in kidney, placenta and brain. Lowest expression in kidney and liver. {ECO:0000269|PubMed:9790768}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Tra-2 (G-20) - sc-51002 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Tra-2β (D-2) - sc-166829 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Tra-2β (D-4) - sc-166769 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

Tra-2β (H-50) - sc-67117 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Tra-2β (S-18) - sc-33318 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-TRA2B antibody - ab123640 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TRA2B antibody [EPR11831] - ab171082 from Abcam Prices $357.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR11831

Anti-TRA2B / SFRS10 Antibody - LS-C10330 from LifeSpan Bioscience Prices $325.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa208-237, AP) - LS-C218092 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa208-237, APC) - LS-C218093 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa208-237, Biotin) - LS-C218094 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa208-237, FITC) - LS-C218095 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa208-237, Azide-free, HRP) - LS-C218096 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa208-237, PE) - LS-C218098 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa64-204, Biotin) - LS-C301255 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa64-204, FITC) - LS-C302210 from LifeSpan Bioscience Prices $485.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa207-237) - LS-C325901 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa64-204) - LS-C296753 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (N-Terminus) - LS-C30697 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa121-170) - LS-C30698 from LifeSpan Bioscience Prices $325.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (aa208-237) - LS-C160153 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-TRA2B / SFRS10 Antibody (clone 7A1) - LS-C198178 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 7A1

TRA2B Antibody - NBP1-57456 from Novus Biologicals Prices $299.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TRA2B Antibody - NBP2-15143 from Novus Biologicals Prices $329.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TRA2B Antibody - NBP1-57457 from Novus Biologicals Prices $139.00, $299.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

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