CLEC12A

Gene Symbol CLEC12A
Entrez Gene 160364
Alt Symbol CLL-1, CLL1, DCAL-2, MICL
Species Human
Gene Type protein-coding
Description C-type lectin domain family 12, member A
Other Description C-type lectin domain family 12 member A|C-type lectin protein CLL-1|C-type lectin-like molecule-1|dendritic cell-associated lectin 2|myeloid inhibitory C-type lectin-like receptor
Swissprots Q6P4H1 B2RA16 Q6RH77 Q6RH78 Q8TDQ6 Q5QGZ9
Accessions CAI45358 CBX47387 EAW96132 EAW96133 Q5QGZ9 AF247788 AAL95693 AK314001 BAG36713 AY426759 AAR84594 AY498550 AAS00605 AY498551 AAS00606 AY498552 AAS00607 AY547296 AAT11783 BC027967 BC063424 AAH63424 BC126289 AAI26290 BC126291 AAI26292 BE242761 BQ017053 CD642076 XM_005253324 XP_005253381 XM_006719033 XP_006719096 XM_006719035 XP_006719098 XM_006719036 XP_006719099 XM_011520570 XP_011518872 XM_011520571 XP_011518873 XM_011520572 XP_011518874 XM_011520573 XP_011518875 NM_001207010 NP_001193939 NM_001300730 NP_001287659 NM_138337 NP_612210 NM_201623 NP_963917 NM_201625
Function Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. {ECO:0000269|PubMed:14739280, ECO:0000269|PubMed:16239426}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:14739280, ECO:0000269|PubMed:15548716, ECO:0000269|PubMed:16239426, ECO:0000269|PubMed:16838277}; Single-pass type II membrane protein {ECO:0000269|PubMed:14739280, ECO:0000269|PubMed:15548716, ECO:0000269|PubMed:16239426, ECO:0000269|PubMed:16838277}. Note=Ligand binding leads to internalization.
Tissue Specificity Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages. {ECO:0000269|PubMed:14739280, ECO:0000269|PubMed:15548716, ECO:0000269|PubMed:16239426, ECO:0000269|PubMed:16838277}.

CLEC-12A CRISPR/Cas9 KO Plasmid (h) - sc-418356 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A HDR Plasmid (h) - sc-418356-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A Double Nickase Plasmid (h) - sc-418356-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A Double Nickase Plasmid (h2) - sc-418356-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A CRISPR Activation Plasmid (h) - sc-418356-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A CRISPR Activation Plasmid (h2) - sc-418356-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A Lentiviral Activation Particles (h) - sc-418356-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A Lentiviral Activation Particles (h2) - sc-418356-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CLEC-12A siRNA (h) - sc-96196 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLEC-12A shRNA Plasmid (h) - sc-96196-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CLEC-12A shRNA (h) Lentiviral Particles - sc-96196-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MICL/CLEC12A RNAi - H00160364-R04 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MICL/CLEC12A RNAi - H00160364-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6198 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6198 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CLEC12A siRNA (Human) - CRJ5900 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MICL/CLEC12A RNAi - H00160364-R06 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CLEC12A - MBS8212935 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CLEC12A (NM_138337.5) - SHH264917 from Creative biogene

Category siRNA
Species Reactivities Human

Human CLEC12A siRNA - orb276401 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CLEC12A shRNA Plasmid (Human) - CHJ5900 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CLEC12A miRNA 3'UTR clone - MiUTR3H-12294 from Creative biogene

Species Reactivities Human

CLEC12A miRNA 3'UTR clone - MiUTR3H-12295 from Creative biogene

Species Reactivities Human
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