Gene Symbol | IL20 |
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Entrez Gene | 50604 |
Alt Symbol | IL-20, IL10D, ZCYTO10 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 20 |
Other Description | cytokine Zcyto10|four alpha helix cytokine|interleukin-20 |
Swissprots | Q2THG6 Q96QZ6 Q17RB3 Q9NYY1 |
Accessions | AAK84423 EAW93520 EAW93521 Q9NYY1 AF224266 AAF36679 AY358320 AAQ88686 AY876922 AAW78348 BC069311 AAH69311 BC069364 AAH69364 BC069398 AAH69398 BC069425 AAH69425 BC069449 AAH69449 BC069487 AAH69487 BC069523 AAH69523 BC069559 AAH69559 BC074948 AAH74948 BC074949 AAH74949 BC117386 AAI17387 BC117390 AAI17391 HQ258739 ADR83490 XM_005273152 XP_005273209 NM_018724 NP_061194 |
Function | Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. {ECO:0000269|PubMed:16511554}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only. {ECO:0000269|PubMed:16908179}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Human-IL20-cDNA-Clone - DC08697 from Abgent, a WuXi AppTec company
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IL20 - MBS1272183 from MyBioSource
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Human IL20 cDNA clone(NM_018724.3) - CDFG002034 from Creative Biomart
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Human IL20 ORF Clone(NM_018724.3) - CDCR304109 from Creative Biomart
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Human IL20 ORF Clone(NM_018724.3) - CDCR304110 from Creative Biomart
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Human IL20 ORF Clone(NM_018724.3) - CDCR304111 from Creative Biomart
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Human IL20 ORF Clone(NM_018724.3) - CDCL167121 from Creative Biomart
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Human interleukin-20 Gene ORF cDNA clone expression plasmid - HG13060-UT from Sino Biological
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Human IL20 ORF Clone(NM_018724.3) - CDCR304109 from Creative biogene
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Human IL20 ORF Clone (BC069311) - CDCS414856 from Creative biogene
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Human IL20 cDNA Clone(NM_018724.3) - CDFG002034 from Creative biogene
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