IL20

Gene Symbol IL20
Entrez Gene 50604
Alt Symbol IL-20, IL10D, ZCYTO10
Species Human
Gene Type protein-coding
Description interleukin 20
Other Description cytokine Zcyto10|four alpha helix cytokine|interleukin-20
Swissprots Q2THG6 Q96QZ6 Q17RB3 Q9NYY1
Accessions AAK84423 EAW93520 EAW93521 Q9NYY1 AF224266 AAF36679 AY358320 AAQ88686 AY876922 AAW78348 BC069311 AAH69311 BC069364 AAH69364 BC069398 AAH69398 BC069425 AAH69425 BC069449 AAH69449 BC069487 AAH69487 BC069523 AAH69523 BC069559 AAH69559 BC074948 AAH74948 BC074949 AAH74949 BC117386 AAI17387 BC117390 AAI17391 HQ258739 ADR83490 XM_005273152 XP_005273209 NM_018724 NP_061194
Function Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. {ECO:0000269|PubMed:16511554}.
Subcellular Location Secreted.
Tissue Specificity Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only. {ECO:0000269|PubMed:16908179}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

IL-20 CRISPR/Cas9 KO Plasmid (h) - sc-405450 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 HDR Plasmid (h) - sc-405450-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 Double Nickase Plasmid (h) - sc-405450-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 Double Nickase Plasmid (h2) - sc-405450-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 CRISPR Activation Plasmid (h) - sc-405450-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 CRISPR Activation Plasmid (h2) - sc-405450-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 Lentiviral Activation Particles (h) - sc-405450-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 Lentiviral Activation Particles (h2) - sc-405450-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

IL-20 siRNA (h) - sc-39660 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-20 shRNA Plasmid (h) - sc-39660-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-20 shRNA (h) Lentiviral Particles - sc-39660-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IL-20 RNAi - H00050604-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU001741 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10604 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10604 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06058 from Sigma-Aldrich

Category miRNA

IL20 siRNA (Human) - CRH9384 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

IL20 - MBS8217956 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human IL20 (NM_018724.3) - SHH318653 from Creative biogene

Category siRNA
Species Reactivities Human

IL20 shRNA Plasmid (Human) - CHH9384 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

IL20 miRNA 3'UTR clone - MiUTR1H-04904 from Creative biogene

Species Reactivities Human
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