Gene Symbol | IL20 |
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Entrez Gene | 50604 |
Alt Symbol | IL-20, IL10D, ZCYTO10 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 20 |
Other Description | cytokine Zcyto10|four alpha helix cytokine|interleukin-20 |
Swissprots | Q2THG6 Q96QZ6 Q17RB3 Q9NYY1 |
Accessions | AAK84423 EAW93520 EAW93521 Q9NYY1 AF224266 AAF36679 AY358320 AAQ88686 AY876922 AAW78348 BC069311 AAH69311 BC069364 AAH69364 BC069398 AAH69398 BC069425 AAH69425 BC069449 AAH69449 BC069487 AAH69487 BC069523 AAH69523 BC069559 AAH69559 BC074948 AAH74948 BC074949 AAH74949 BC117386 AAI17387 BC117390 AAI17391 HQ258739 ADR83490 XM_005273152 XP_005273209 NM_018724 NP_061194 |
Function | Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. {ECO:0000269|PubMed:16511554}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only. {ECO:0000269|PubMed:16908179}. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
Active human IL20 full length protein - ab201402 from Abcam
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Active human IL20 full length protein - ab49819 from Abcam
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Active mouse IL20 full length protein - ab51977 from Abcam
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Active mouse IL20 full length protein - ab73330 from Abcam
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Active rat IL20 full length protein - ab191764 from Abcam
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Human IL20 full length protein - ab151931 from Abcam
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Human IL20 protein fragment - ab194038 from Abcam
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Recombinant Human IL-20 Protein - NBP2-35056 from Novus Biologicals
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IL-20 Partial Recombinant Protein - H00050604-Q01 from Novus Biologicals
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IL-20 Recombinant Protein - H00050604-P01 from Novus Biologicals
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IL-20 Recombinant Protein - P4411 from Novus Biologicals
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Recombinant Human IL-20 Protein - NBP1-99230 from Novus Biologicals
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IL-20 Protein - NBP1-99694 from Novus Biologicals
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IL20 recombinant protein - GTX65423 from GeneTex
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IL20 Recombinant Protein (Active) - GTX48263-PRO from GeneTex
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Recombinant Human IL-20 - 1102-IL-025 from R&D Systems
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Recombinant Human IL-20, CF - 1102-IL-025/CF from R&D Systems
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IL 20 Protein (OPPA00610) - OPPA00610 from Aviva Systems Biology
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Recombinant IL-20 (OPSD00055) - OPSD00055 from Aviva Systems Biology
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Human IL20 protein - orb80079 from Biorbyt
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Human IL20 protein (Native) - orb139171 from Biorbyt
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Mouse IL20 protein - orb80469 from Biorbyt
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IL20 protein - 30R-2634 from Fitzgerald
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Interleukin-20 / IL20 - PA200 from Acris Antibodies
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Interleukin-20 / IL20 - PA200X from Acris Antibodies
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