IL20

Gene Symbol IL20
Entrez Gene 50604
Alt Symbol IL-20, IL10D, ZCYTO10
Species Human
Gene Type protein-coding
Description interleukin 20
Other Description cytokine Zcyto10|four alpha helix cytokine|interleukin-20
Swissprots Q2THG6 Q96QZ6 Q17RB3 Q9NYY1
Accessions AAK84423 EAW93520 EAW93521 Q9NYY1 AF224266 AAF36679 AY358320 AAQ88686 AY876922 AAW78348 BC069311 AAH69311 BC069364 AAH69364 BC069398 AAH69398 BC069425 AAH69425 BC069449 AAH69449 BC069487 AAH69487 BC069523 AAH69523 BC069559 AAH69559 BC074948 AAH74948 BC074949 AAH74949 BC117386 AAI17387 BC117390 AAI17391 HQ258739 ADR83490 XM_005273152 XP_005273209 NM_018724 NP_061194
Function Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. {ECO:0000269|PubMed:16511554}.
Subcellular Location Secreted.
Tissue Specificity Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only. {ECO:0000269|PubMed:16908179}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

IL-20 (C-15) - sc-16732 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IL-20 (PL-C21) - sc-134365 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
IL-20 (PL-C21): sc-134365. Western blot analysis of IL-20 expression in K-562 whole cell lysate.

Anti-IL20 antibody - ab106279 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IL20 antibody (ab106279) at 1/500 dilution + Jurkat cell lysate

Anti-IL20 antibody - ab17426 from Abcam

Prices $370.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
IHC image of ab17426 staining in human normal pancreas formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab17426, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-IL20 antibody - ab57227 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IL20 antibody [15] - ab51708 from Abcam

Host Mouse
Clonality Monoclonal
Clone 15
All lanes : Anti-IL20 antibody [15] (ab51708) at 1/1000 dilutionLane 1 : Human skin whole tissue lysateLane 2 : Human skin whole tissue lysateLane 3 : Human skin whole tissue lysateLysates/proteins at 30 µg per lane.SecondaryHRP-conjugated Horse anti-mouse IgG polyclonal at 1/2000 dilutionPerformed under reducing conditions.

Anti-IL20 antibody [2B1] - ab180477 from Abcam

Prices $357.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B1
All lanes : Anti-IL20 antibody [2B1] (ab180477) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY IL20 cDNALysates/proteins at 5 µg per lane.

Anti-IL20 antibody (Biotin) - ab17478 from Abcam

Prices $370.00
Sizes 25 µg
Host Goat
Clonality Polyclonal

Anti-IL20 Antibody - LS-C96114 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-IL20 Antibody (aa25-176) - LS-C70980 from LifeSpan Bioscience

Prices $575.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-IL20 Antibody (Biotin) - LS-C104573 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 25 µg, 50 µg
Host Goat
Clonality Polyclonal

Anti-IL20 Antibody - LS-C311299 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL20 Antibody (aa67-177) - LS-C308505 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-IL20 Antibody (aa67-177, Azide-free) - LS-C330479 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-IL20 Antibody (Asp61) - LS-C177529 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of IL-20 (D61) pAb in extracts from A549 cells.

Anti-IL20 Antibody (aa25-176) - LS-C314880 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant IL20.

Anti-IL20 Antibody (aa12-61) - LS-C199904 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of IL-20 antibody in extracts from A549 cells.

Anti-IL20 Antibody (aa25-176, clone 5E10) - LS-C336845 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5E10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL20 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL20.

Anti-IL20 Antibody (aa25-176, clone 4C2) - LS-C338700 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4C2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL20 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL20.

Anti-IL20 Antibody (aa25-176, clone 2B1) - LS-C336848 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B1
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IL20 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-IL20 Antibody - LS-C334840 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of A549 cell using IL20 antibody. Blue: DAPI for nuclear staining.

Anti-IL20 Antibody (aa25-176, clone 3E5) - LS-C338701 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3E5
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL20 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL20.

Anti-IL20 Antibody (aa25-176, clone 6C9) - LS-C338740 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6C9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL20 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL20.

Anti-IL20 Antibody (aa25-176, clone 6H7) - LS-C338739 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6H7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL20 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL20.

Anti-IL20 Antibody - LS-C104598 from LifeSpan Bioscience

Prices $285.00, $325.00
Sizes 50 µg, 100 µg
Host Goat
Clonality Polyclonal
Western Blot (non-reducing) of IL-20 antibody LS-C104598
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