Gene Symbol | PIN4 |
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Entrez Gene | 5303 |
Alt Symbol | EPVH, PAR14, PAR17 |
Species | Human |
Gene Type | protein-coding |
Description | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
Other Description | PPIase PIN4|eukaryotic parvulin homolog|hEPVH|hPar14|hPar17|parvulin|parvulin-14|parvulin-17|peptidyl-prolyl cis-trans isomerase NIMA-interacting 4|peptidyl-prolyl cis-trans isomerase Pin4|peptidyl-prolyl cis/trans isomerase EPVH|peptidylprolyl cis/trans isomerase NIMA-interacting, 4|protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)|rotamase PIN4 |
Swissprots | A8E0G6 Q9Y237 Q52M21 F5H1P5 Q3MHV0 Q0D2H3 Q5HYW6 B3KXM0 Q6IRW4 |
Accessions | CAM12362 CAM12363 CAM12364 EAW71812 Q9Y237 AB009690 BAA82320 AF143096 AAD27893 AK127605 BAG54532 AU098526 AV709926 BC005234 AAH05234 BC070288 AAH70288 BC093700 AAH93700 BC104653 AAI04654 BC111394 AAI11395 BC112281 AAI12282 BE504461 BU952002 HQ258728 ADR83479 NM_001170747 NP_001164218 NM_006223 NP_006214 NR_033187 |
Function | Isoform 1 is involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double-stranded DNA. {ECO:0000269|PubMed:19369196}. |
Subcellular Location | Isoform 1: Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Colocalizes in the nucleolus during interphase and on the spindle apparatus during mitosis with NPM1. |
Tissue Specificity | Isoform 2 is much more stable than isoform 1 (at protein level). Ubiquitous. Isoform 1 and isoform 2 are expressed in kidney, liver, blood vessel, brain, mammary gland, skeletal muscle, small intestine and submandibularis. Isoform 1 transcripts are much more abundant than isoform 2 in each tissue analyzed. {ECO:0000269|PubMed:10100858, ECO:0000269|PubMed:10364457, ECO:0000269|PubMed:16522211}. |
Active human PIN4 full length protein - ab168039 from Abcam
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Active human PIN4 full length protein - ab105618 from Abcam
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Human PIN4 full length protein - ab186986 from Abcam
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PIN4 Antibody Blocking Peptide - LS-E5982 from LifeSpan Bioscience
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PIN4 Antibody Blocking Peptide - LS-E20618 from LifeSpan Bioscience
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PIN4 Antibody Blocking Peptide - LS-E20619 from LifeSpan Bioscience
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PIN4 Partial Recombinant Protein - H00005303-Q01 from Novus Biologicals
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PIN4 Recombinant Protein - H00005303-P01 from Novus Biologicals
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PIN4 Protein - NBP1-51068 from Novus Biologicals
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PIN4-Antibody-N-term-Blocking-Peptide - BP18546a from Abgent, a WuXi AppTec company
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Human PIN4 protein - orb169031 from Biorbyt
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Human PIN4 protein - orb180367 from Biorbyt
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PIN4 Blocking Peptide - 33R-6296 from Fitzgerald
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PIN4 Blocking Peptide - 33R-5002 from Fitzgerald
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PIN4 protein (His tag) - 80R-1756 from Fitzgerald
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Human PIN4 Protein - abx068457 from Abbexa
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PIN4 (1-156, His-tag) - AR09938PU-L from Acris Antibodies
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PIN4 (1-156, His-tag) - AR09938PU-N from Acris Antibodies
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PIN4 - H00005303-P01-10 from Acris Antibodies
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PIN4 - H00005303-P01-25 from Acris Antibodies
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PIN4 - H00005303-Q01-10 from Acris Antibodies
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PIN4 - H00005303-Q01-25 from Acris Antibodies
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Peptidyl-Prolyl Cis/Trans Isomerase NIMA-Interacting 4, Human Recombinant - 228-12258-1 from RayBiotech
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Peptidyl Prolyl Cis/Trans Isomerase NIMA Interacting Protein 4 (PIN4), Human - 20-7772 from ARP American Research Products
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PIN4, 1-156aa, Human, His tag, E.coli - 01-2201-4 from ARP American Research Products
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