PIN4

Gene Symbol PIN4
Entrez Gene 5303
Alt Symbol EPVH, PAR14, PAR17
Species Human
Gene Type protein-coding
Description peptidylprolyl cis/trans isomerase, NIMA-interacting 4
Other Description PPIase PIN4|eukaryotic parvulin homolog|hEPVH|hPar14|hPar17|parvulin|parvulin-14|parvulin-17|peptidyl-prolyl cis-trans isomerase NIMA-interacting 4|peptidyl-prolyl cis-trans isomerase Pin4|peptidyl-prolyl cis/trans isomerase EPVH|peptidylprolyl cis/trans isomerase NIMA-interacting, 4|protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)|rotamase PIN4
Swissprots A8E0G6 Q9Y237 Q52M21 F5H1P5 Q3MHV0 Q0D2H3 Q5HYW6 B3KXM0 Q6IRW4
Accessions CAM12362 CAM12363 CAM12364 EAW71812 Q9Y237 AB009690 BAA82320 AF143096 AAD27893 AK127605 BAG54532 AU098526 AV709926 BC005234 AAH05234 BC070288 AAH70288 BC093700 AAH93700 BC104653 AAI04654 BC111394 AAI11395 BC112281 AAI12282 BE504461 BU952002 HQ258728 ADR83479 NM_001170747 NP_001164218 NM_006223 NP_006214 NR_033187
Function Isoform 1 is involved as a ribosomal RNA processing factor in ribosome biogenesis. Binds to tightly bent AT-rich stretches of double-stranded DNA. {ECO:0000269|PubMed:19369196}.
Subcellular Location Isoform 1: Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Note=Colocalizes in the nucleolus during interphase and on the spindle apparatus during mitosis with NPM1.
Tissue Specificity Isoform 2 is much more stable than isoform 1 (at protein level). Ubiquitous. Isoform 1 and isoform 2 are expressed in kidney, liver, blood vessel, brain, mammary gland, skeletal muscle, small intestine and submandibularis. Isoform 1 transcripts are much more abundant than isoform 2 in each tissue analyzed. {ECO:0000269|PubMed:10100858, ECO:0000269|PubMed:10364457, ECO:0000269|PubMed:16522211}.

Anti-PIN4 antibody - ab98130 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PIN4 antibody (ab98130) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg

Anti-PIN4 antibody [EPR10033] - ab155283 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10033
All lanes : Anti-PIN4 antibody [EPR10033] (ab155283) at 1/1000 dilutionLane 1 : 293T lysateLane 2 : Human skeletal muscle lysateLane 3 : Human fetal liver lysateLane 4 : Mouse liver lysateLane 5 : HepG2 lysateLane 6 : RAW264.7 lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-PIN4 antibody - N-terminal - ab185518 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin fixed and paraffin embedded Human esophagus tissue labeling PIN4 with ab185518 at a 1/500 dilution.

Anti-PIN4 Antibody (aa6-32, AP) - LS-C239074 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa6-32, APC) - LS-C239075 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa6-32, Biotin) - LS-C239078 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa6-32, FITC) - LS-C239079 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa6-32, PE) - LS-C239080 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa6-32, Azide-free, HRP) - LS-C248479 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa23-130, Biotin) - LS-C297221 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa23-130, FITC) - LS-C303389 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa5-32) - LS-C324053 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PIN4 Antibody (aa61-157, Azide-free) - LS-C328249 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-PIN4 Antibody (C-Terminus) - LS-C107715 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PIN4 antibody LS-C107715 Western blot of 721_B cell lysate.

Anti-PIN4 Antibody (N-Terminus) - LS-C107714 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PIN4 antibody LS-C107714 Western blot of 293T cell lysate.

Anti-PIN4 Antibody (aa6-32) - LS-C158662 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PIN4 Antibody western blot of MDA-MB231 cell line lysates (35 ug/lane). The PIN4 antibody detected the PIN4 protein (arrow).

Anti-PIN4 Antibody (aa23-130) - LS-C295791 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PIN4.

Anti-PIN4 Antibody (clone 7H2) - LS-C340496 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7H2
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PIN4 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)(1:150).

PIN4 Antibody - NBP1-52995 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PIN4 Antibody [NBP1-52995] - 721_B cell lysate, concentration 0.2-1 ug/ml.

PIN4 Antibody - NBP1-52994 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 50 µl
Host Rabbit
Clonality Polyclonal

PIN4 Antibody - H00005303-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PIN4 Antibody [H00005303-D01P] - Analysis of PIN4 expression in transfected 293T cell line by PIN4 polyclonal antibody.Lane 1: PIN4 transfected lysate(16.60 KDa).Lane 2: Non-transfected lysate.

PIN4 Antibody - H00005303-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-PIN4 antibody produced in rabbit - SAB2104910 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PIN4, antibody produced in rabbit: <B>Cat. No. SAB2104910</B>: Immunoblotting analysis of PIN4 in 721_B cell lysate with PIN4 anitbody at 1 μg/mL.

Anti-PIN4, (N-terminal) antibody produced in rabbit - SAB2104909 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PIN4, antibody produced in rabbit: <B>Cat. No. SAB2104909</B>: Immunoblotting analysis of PIN4 in 293T cell lysate with PIN4 anitbody at 1 μg/mL.

Anti-PIN4 antibody produced in rabbit - HPA054483 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PIN4: <B>Cat. No. HPA054483</B>: Immunohistochemical staining of human esophagus shows moderate cytoplasmic and nuclear positivity in squamous epithelial cells.
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