AEN

Gene Symbol AEN
Entrez Gene 64782
Alt Symbol ISG20L1, pp12744
Species Human
Gene Type protein-coding
Description apoptosis enhancing nuclease
Other Description apoptosis-enhancing nuclease|interferon stimulated exonuclease gene 20kDa-like 1|interferon-stimulated 20 kDa exonuclease-like 1
Swissprots C9J571 Q9H9X7 Q8WTP8 Q9BSA5
Accessions CCQ43693 EAX02009 EAX02010 EAX02011 Q8WTP8 AB209323 BAD92560 AF318330 AAL55837 AF327352 AAL56012 AK022546 BAB14091 AK022624 AK308119 BC005164 AAH05164 BC014407 AAH14407 BC020988 AAH20988 CA441442 HQ447809 ADQ32293 XM_005254966 XP_005255023 XM_005254967 XP_005255024 XM_006720645 XP_006720708 XM_011521905 XP_011520207 NM_022767 NP_073604
Function Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis. {ECO:0000269|PubMed:16171785, ECO:0000269|PubMed:18264133}.
Subcellular Location Nucleus. Nucleus, nucleolus. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction.

ISG20L1 (D-20) - sc-243108 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ISG20L1 (H-75) - sc-368705 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ISG20L1 (P-17) - sc-243107 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Apoptosis enhancing nuclease antibody - ab97915 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Apoptosis enhancing nuclease antibody (ab97915) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-Apoptosis enhancing nuclease antibody - ab68736 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Apoptosis enhancing nuclease antibody (ab68736) at 1/500 dilutionLane 1 : Apoptosis enhancing nuclease transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-AEN Antibody - LS-C308530 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-AEN Antibody (aa236-325) - LS-C186244 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded Cal27 Xenograft using Apoptosis-enhancing nuclease antibody at 1:100 dilution.

Apoptosis enhancing nuclease Antibody - NBP2-14272 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: Apoptosis enhancing nuclease Antibody [NBP2-14272] - Staining of human cell line Hep-G2 shows positivity in nucleus but not nucleoli.

Apoptosis enhancing nuclease Antibody - NBP1-31700 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Apoptosis enhancing nuclease Antibody [NBP1-31700] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE; antibody diluted at 1:1000.

Apoptosis enhancing nuclease Antibody - H00064782-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Apoptosis enhancing nuclease Antibody [H00064782-B01P] - Analysis of AEN expression in transfected 293T cell line by AEN polyclonal antibody. Lane 1: ISG20L1 transfected lysate(35.75 KDa). Lane 2: Non-transfected lysate.

Apoptosis enhancing nuclease Antibody - bs-7604R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit

Anti-AEN antibody produced in rabbit - HPA048599 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AEN:<B>Cat. No. HPA048599</B>: Immunohistochemical staining of human skin shows strong cytoplasmic and nuclear positivity in melanocytes.

Anti-ISG20L1 antibody produced in mouse - SAB1400678 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-ISG20L1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400678</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.

Anti-AEN (C-terminal) antibody produced in rabbit - SAB2700454 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AEN (C-terminal): <B>Cat. No. SAB2700454</B>: Immunohistochemical analysis of paraffin-embedded Cal27 Xenograft, using Apoptosis-enhancing nuclease antibody at 1:100 dilution.

Apoptosis-enhancing nuclease antibody [C2C3], C-term - GTX112086 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-Apoptosis-enhancing nuclease antibody [C2C3], C-term used in ICC/IF. GTX112086

Apoptosis enhancing nuclease antibody - orb73850 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:Hela whole cell lysate using Apoptosis enhancing nuclease antibody

AEN antibody (OAGA00945) - OAGA00945 from Aviva Systems Biology

Prices $340.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Apoptosis enhancing nuclease antibody - 70R-13466 from Fitzgerald

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

AEN / ISG20L1 antibody - H00064782-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Immunofluorescence of purified MaxPab antibody to ISG20L1 on HeLa cell. [antibody concentration 10 ug/ml]

AEN antibody - 12337-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

Apoptosis-enhancing nuclease - MBS272802 from MyBioSource

Prices $360.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Diluted at 1:1000

Apoptosis-enhancing nuclease antibody - 22725 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE Primary antibody diluted at 1: 1000

AEN, Polyclonal Antibody - MBS2527967 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal
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