AEN

Gene Symbol AEN
Entrez Gene 64782
Alt Symbol ISG20L1, pp12744
Species Human
Gene Type protein-coding
Description apoptosis enhancing nuclease
Other Description apoptosis-enhancing nuclease|interferon stimulated exonuclease gene 20kDa-like 1|interferon-stimulated 20 kDa exonuclease-like 1
Swissprots C9J571 Q9H9X7 Q8WTP8 Q9BSA5
Accessions CCQ43693 EAX02009 EAX02010 EAX02011 Q8WTP8 AB209323 BAD92560 AF318330 AAL55837 AF327352 AAL56012 AK022546 BAB14091 AK022624 AK308119 BC005164 AAH05164 BC014407 AAH14407 BC020988 AAH20988 CA441442 HQ447809 ADQ32293 XM_005254966 XP_005255023 XM_005254967 XP_005255024 XM_006720645 XP_006720708 XM_011521905 XP_011520207 NM_022767 NP_073604
Function Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis. {ECO:0000269|PubMed:16171785, ECO:0000269|PubMed:18264133}.
Subcellular Location Nucleus. Nucleus, nucleolus. Note=Localized predomintly in the nucleolus. Translocates from the nucleolus to the nucleoplasm upon apoptosis induction.

ISG20L1 CRISPR/Cas9 KO Plasmid (h) - sc-410104 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 HDR Plasmid (h) - sc-410104-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 Double Nickase Plasmid (h) - sc-410104-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 Double Nickase Plasmid (h2) - sc-410104-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 CRISPR Activation Plasmid (h) - sc-410104-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 CRISPR Activation Plasmid (h2) - sc-410104-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 Lentiviral Activation Particles (h) - sc-410104-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 Lentiviral Activation Particles (h2) - sc-410104-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ISG20L1 siRNA (h) - sc-89904 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ISG20L1 shRNA Plasmid (h) - sc-89904-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ISG20L1 shRNA (h) Lentiviral Particles - sc-89904-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU022001 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2910 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2910 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10798 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10798

AEN siRNA (Human) - CRJ2087 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AEN - MBS8231774 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AEN (NM_022767.3) - SHH232870 from Creative biogene

Category siRNA
Species Reactivities Human

Human AEN siRNA - orb272588 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AEN shRNA Plasmid (Human) - CHJ2087 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AEN miRNA 3'UTR clone - MiUTR4H-TG00196 from Creative biogene

Species Reactivities Human
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