SETDB2

Gene Symbol	SETDB2
Entrez Gene	83852
Alt Symbol	C13orf4, CLLD8, CLLL8, KMT1F
Species	Human
Gene Type	protein-coding
Description	SET domain, bifurcated 2
Other Description	chronic lymphocytic leukemia deletion region 8|chronic lymphocytic leukemia deletion region gene 8 protein|histone-lysine N-methyltransferase SETDB2|lysine N-methyltransferase 1F
Swissprots	Q96AI6 Q86UD6 Q5TC65 Q659A7 Q5W0A7 Q5TC66 Q96T68
Accessions	EAX08824 EAX08825 EAX08826 Q96T68 AB209349 BAD92586 AF086317 AF277186 AF334407 AAK38373 AK307593 AK308220 AK308354 AK311602 AL831937 CAH56265 AL833957 CAD38807 AW297242 BC017078 AAH17078 BC028202 BC047434 AAH47434 DB164537 XM_005266568 XP_005266625 XM_005266569 XP_005266626 XM_005266572 XP_005266629 XM_011535269 XP_011533571 XM_011535270 XP_011533572 XM_011535271 XP_011533573 XM_011535272 XP_011533574 XM_011535273 XP_011533575 XM_011535274 XP_011533576 XM_011535275 XP_011533577 XM_011535276 XP_011533578 XM_011535277 XP_011533579 XR_941678 XR_941680 NM_001160308 NP_001153780 NM_031915 NP_114121
Function	Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis. {ECO:0000269|PubMed:20404330}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:20404330}. Chromosome {ECO:0000305|PubMed:20404330}.
Tissue Specificity	Ubiquitous. Highest expression in heart, testis and ovary.
Top Pathways	Lysine degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SETDB2 - MBS1269570 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC047434

Human SETDB2 cDNA clone(NM_001160308.1) - CDFH017327 from Creative Biomart Species Human Accession NM_001160308.1

Human SETDB2 ORF Clone(NM_001160308.1) - CDCL175178 from Creative Biomart Species Human Accession NM_001160308.1

Human SETDB2 ORF Clone(NM_001160308.1) - CDCR353935 from Creative Biomart Species Human Accession NM_001160308.1

Human SETDB2 ORF Clone(NM_001160308.1) - CDCR353939 from Creative Biomart Species Human Accession NM_001160308.1

human SETDB2 ORF clone - CDCH079072 from Creative Biomart Species Human Accession NM_001160308

human SETDB2 ORF clone - CDCH079073 from Creative Biomart Species Human Accession NM_001160308

human SETDB2 ORF clone - CDCH079074 from Creative Biomart Species Human Accession NM_001160308

human SETDB2 ORF clone - CDCH079075 from Creative Biomart Species Human Accession NM_001160308

human SETDB2 ORF clone - CDCH079076 from Creative Biomart Species Human Accession NM_001160308

human SETDB2 ORF clone - CDCH079077 from Creative Biomart Species Human Accession NM_001160308

Human SETDB2 Gene ORF cDNA clone in cloning vector - HG15201-G from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG15201-NY from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, N-His tag - HG15201-NH from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG15201-NF from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG15201-ACR from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG15201-ANR from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG15201-ANG from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, C-His tag - HG15201-CH from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG15201-CF from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG15201-NM from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG15201-CM from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG15201-CY from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid - HG15201-UT from Sino Biological Species Human

Human SETDB2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG15201-ACG from Sino Biological Species Human

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