MED1

Gene Symbol	MED1
Entrez Gene	5469
Alt Symbol	CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2
Species	Human
Gene Type	protein-coding
Description	mediator complex subunit 1
Other Description	ARC205|PPAR binding protein|PPAR-binding protein|PPARG binding protein|TR-interacting protein 2|TRIP-2|activator-recruited cofactor 205 kDa component|mediator of RNA polymerase II transcription subunit 1|p53 regulatory protein RB18A|peroxisome proliferator-activated receptor-binding protein|thyroid hormone receptor-associated protein complex 220 kDa component|thyroid hormone receptor-associated protein complex component TRAP220|thyroid receptor interacting protein 2|thyroid receptor-interacting protein 2|vitamin D receptor-interacting protein 230 kD|vitamin D receptor-interacting protein complex component DRIP205
Swissprots	O75447 O43810 A2RRQ6 Q9HD39 Q6PK58 Q6P9H7 Q15648
Accessions	EAW60575 Q15648 AF055994 AAC39854 AF283812 AAF98352 AK299789 BAG61669 AK314185 BAG36866 BC006517 AAH06517 BC060758 AAH60758 BC131783 AAI31784 BP357374 JF432429 ADZ15646 L40366 AAC41736 Y13467 CAA73867 XM_005257465 XP_005257522 XM_006721957 XP_006722020 NM_004774 NP_004765
Function	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:10406464, ECO:0000269|PubMed:11867769, ECO:0000269|PubMed:12037571, ECO:0000269|PubMed:12218053, ECO:0000269|PubMed:12556447, ECO:0000269|PubMed:14636573, ECO:0000269|PubMed:15340084, ECO:0000269|PubMed:15471764, ECO:0000269|PubMed:15989967, ECO:0000269|PubMed:16574658, ECO:0000269|PubMed:9653119}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:15471764, ECO:0000269|PubMed:16314496, ECO:0000269|PubMed:16574658}. Note=A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:9444950, ECO:0000269|PubMed:9653119}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MED1 - MBS1272533 from MyBioSource Species Human Accession BC131783

MED1 - MBS1278426 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC060758

Human MED1 ORF clone(NM_004774.3) - CDCL185312 from Creative Biomart Species Human Accession NM_004774.3

Human MED1 Gene ORF cDNA clone in cloning vector - HG13221-G from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid - HG13221-UT from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13221-ANG from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13221-CY from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13221-NY from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13221-NF from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13221-NH from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13221-NM from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13221-CF from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13221-ACG from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13221-CM from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid - HG13221-G-N from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13221-ACR from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13221-ANR from Sino Biological Species Human

Human MED1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13221-CH from Sino Biological Species Human

Human MED1 ORF clone(NM_004774.3) - CDCL185312 from Creative biogene Species Human

Human MED1 ORF Clone (BC060758) - CDCS411948 from Creative biogene Species Human Accession Q15648

Human MED1 ORF Clone (BC131783) - CDCS411949 from Creative biogene Species Human Accession Q15648

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