MED1

Gene Symbol MED1
Entrez Gene 5469
Alt Symbol CRSP1, CRSP200, DRIP205, DRIP230, PBP, PPARBP, PPARGBP, RB18A, TRAP220, TRIP2
Species Human
Gene Type protein-coding
Description mediator complex subunit 1
Other Description ARC205|PPAR binding protein|PPAR-binding protein|PPARG binding protein|TR-interacting protein 2|TRIP-2|activator-recruited cofactor 205 kDa component|mediator of RNA polymerase II transcription subunit 1|p53 regulatory protein RB18A|peroxisome proliferator-activated receptor-binding protein|thyroid hormone receptor-associated protein complex 220 kDa component|thyroid hormone receptor-associated protein complex component TRAP220|thyroid receptor interacting protein 2|thyroid receptor-interacting protein 2|vitamin D receptor-interacting protein 230 kD|vitamin D receptor-interacting protein complex component DRIP205
Swissprots O75447 O43810 A2RRQ6 Q9HD39 Q6PK58 Q6P9H7 Q15648
Accessions EAW60575 Q15648 AF055994 AAC39854 AF283812 AAF98352 AK299789 BAG61669 AK314185 BAG36866 BC006517 AAH06517 BC060758 AAH60758 BC131783 AAI31784 BP357374 JF432429 ADZ15646 L40366 AAC41736 Y13467 CAA73867 XM_005257465 XP_005257522 XM_006721957 XP_006722020 NM_004774 NP_004765
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:10406464, ECO:0000269|PubMed:11867769, ECO:0000269|PubMed:12037571, ECO:0000269|PubMed:12218053, ECO:0000269|PubMed:12556447, ECO:0000269|PubMed:14636573, ECO:0000269|PubMed:15340084, ECO:0000269|PubMed:15471764, ECO:0000269|PubMed:15989967, ECO:0000269|PubMed:16574658, ECO:0000269|PubMed:9653119}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15471764, ECO:0000269|PubMed:16314496, ECO:0000269|PubMed:16574658}. Note=A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:9444950, ECO:0000269|PubMed:9653119}.

Mouse/Human MED1 / TRAP220 ELISA Kit (Cell-Based ELISA) - LS-F3208 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

Rabbit anti-CRSP1/TRAP220 Antibody, Affinity Purified - PLA0142 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

Goat anti-CRSP1/TRAP220 Antibody, Affinity Purified - PLA0300 from Sigma-Aldrich

Prices $323.50
Sizes 100 µl
<B>Immunofluorescence</B>: This antibody is qualified for the Proximity Ligation Assay (PLA). The above image shows representative results for PLA using three color fluorescence, including DAPI stained nuclei (blue), phalloidin stained cytoplasmic F-actin (green), and PLA positive signal (red).

mediator complex subunit 1, ELISA Kit - MBS9322823 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7248653 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7220240 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7222561 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7251005 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7248227 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

MED1 Colorimetric Cell-Based ELISA - CB6026 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7214764 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7252404 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7200999 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7207552 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7236721 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Mediator of RNA polymerase II transcription subunit 1 (MED1), ELISA Kit - MBS7222382 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Mediator of RNA polymerase II transcription subunit 1 (MED1) ELISA Kit - AE33903HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
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