DCTN2

Gene Symbol	DCTN2
Entrez Gene	10540
Alt Symbol	DCTN50, DYNAMITIN, HEL-S-77, RBP50
Species	Human
Gene Type	protein-coding
Description	dynactin 2 (p50)
Other Description	50 kD dynein-associated polypeptide|50 kDa dynein-associated polypeptide|dynactin complex 50 kD subunit|dynactin complex 50 kDa subunit|dynactin subunit 2|epididymis secretory protein Li 77|p50 dynamitin
Swissprots	Q9BW17 Q86YN2 B2RBK5 Q13561
Accessions	EAW97027 EAW97028 EAW97029 Q13561 AK055682 BAG51555 AK096242 BAG53236 AK098794 AK222693 BAD96413 AK292364 BAF85053 AK314705 BAG37252 AY189155 AAO34395 BC000718 AAH00718 BC009468 AAH09468 BC014083 AAH14083 DB027733 DB569305 FJ224315 ACI46007 HQ447201 ADQ31688 U50733 AAC50423 XM_011537761 XP_011536063 XR_944481 NM_001261412 NP_001248341 NM_001261413 NP_001248342 NM_006400 NP_006391
Function	Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:8647893}. Membrane {ECO:0000269|PubMed:8647893}; Peripheral membrane protein {ECO:0000269|PubMed:8647893}.
Top Pathways	Huntington's disease, Vasopressin-regulated water reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DCTN2 cDNA Clone - orb142799 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-DCTN2-cDNA-Clone - DC00347 from Abgent, a WuXi AppTec company Prices $541.35 Sizes 10 µg Species Human Accession BC000718

DCTN2 - MBS1277829 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC000718

Human DCTN2 ORF Clone(NM_001261412.1) - CDCL160681 from Creative Biomart Species Human Accession NM_001261412.1

Human DCTN2 ORF Clone(NM_006400.4) - CDCL160682 from Creative Biomart Species Human Accession NM_006400.4

Human DCTN2 Gene cDNA clone plasmid - HG14449-G from Sino Biological Species Human

Human DCTN2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-His-tagged - HG14449-NH from Sino Biological Species Human Accession BC000718

Human DCTN2 natural ORF mammalian expression plasmid, C-Myc tag - HG14449-CM from Sino Biological Species Human Accession BC000718

Human DCTN2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-HA-tagged - HG14449-NY from Sino Biological Species Human Accession BC000718

Human DCTN2 natural ORF mammalian expression plasmid, C-GFPSpark tag - HG14449-ACG from Sino Biological Species Human Accession BC000718

Human DCTN2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-His-tagged - HG14449-CH from Sino Biological Species Human Accession BC000718

Human DCTN2 natural ORF mammalian expression plasmid, C-OFPSpark / RFP tag - HG14449-ACR from Sino Biological Species Human Accession BC000718

Human DCTN2 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG14449-UT from Sino Biological Species Human Accession BC000718

Human DCTN2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-HA-tagged - HG14449-CY from Sino Biological Species Human Accession BC000718

Human DCTN2 natural ORF mammalian expression plasmid, N-Flag tag - HG14449-NF from Sino Biological Species Human Accession BC000718

Human DCTN2 Gene cDNA Clone (full-length ORF Clone), expression ready, C-FLAG-tagged - HG14449-CF from Sino Biological Species Human Accession BC000718

Human DCTN2 Gene cDNA Clone (full-length ORF Clone), expression ready, N-Myc-tagged - HG14449-NM from Sino Biological Species Human Accession BC000718

Human DCTN2 ORF Clone (BC000718) - CDCS412716 from Creative biogene Species Human Accession Q13561

Human DCTN2 ORF clone (BC000718) - CDCB158927 from Creative biogene Species Human

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