DCTN2

Gene Symbol DCTN2
Entrez Gene 10540
Alt Symbol DCTN50, DYNAMITIN, HEL-S-77, RBP50
Species Human
Gene Type protein-coding
Description dynactin 2 (p50)
Other Description 50 kD dynein-associated polypeptide|50 kDa dynein-associated polypeptide|dynactin complex 50 kD subunit|dynactin complex 50 kDa subunit|dynactin subunit 2|epididymis secretory protein Li 77|p50 dynamitin
Swissprots Q9BW17 Q86YN2 B2RBK5 Q13561
Accessions EAW97027 EAW97028 EAW97029 Q13561 AK055682 BAG51555 AK096242 BAG53236 AK098794 AK222693 BAD96413 AK292364 BAF85053 AK314705 BAG37252 AY189155 AAO34395 BC000718 AAH00718 BC009468 AAH09468 BC014083 AAH14083 DB027733 DB569305 FJ224315 ACI46007 HQ447201 ADQ31688 U50733 AAC50423 XM_011537761 XP_011536063 XR_944481 NM_001261412 NP_001248341 NM_001261413 NP_001248342 NM_006400 NP_006391
Function Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:8647893}. Membrane {ECO:0000269|PubMed:8647893}; Peripheral membrane protein {ECO:0000269|PubMed:8647893}.
Top Pathways Huntington's disease, Vasopressin-regulated water reabsorption

Dynactin 2 CRISPR/Cas9 KO Plasmid (h) - sc-406486 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 HDR Plasmid (h) - sc-406486-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 Double Nickase Plasmid (h) - sc-406486-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 Double Nickase Plasmid (h2) - sc-406486-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 CRISPR Activation Plasmid (h) - sc-406486-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 CRISPR Activation Plasmid (h2) - sc-406486-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 Lentiviral Activation Particles (h) - sc-406486-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 Lentiviral Activation Particles (h2) - sc-406486-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dynactin 2 siRNA (h) - sc-95708 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dynactin 2 shRNA Plasmid (h) - sc-95708-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dynactin 2 shRNA (h) Lentiviral Particles - sc-95708-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dynactin Subunit 2/DCTN2/DCTN-50 RNAi - H00010540-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU086581 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7004 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7004 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03078 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03078

DCTN2 siRNA (Human) - CRH7165 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DCTN2 - MBS8201952 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DCTN2 (NM_006400.4) - SHH275369 from Creative biogene

Category siRNA
Species Reactivities Human

Human DCTN2 siRNA - orb267667 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DCTN2 shRNA Plasmid (Human) - CHH7165 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DCTN2 miRNA 3'UTR clone - MiUTR3H-09181 from Creative biogene

Species Reactivities Human
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