DCTN2

Gene Symbol	DCTN2
Entrez Gene	10540
Alt Symbol	DCTN50, DYNAMITIN, HEL-S-77, RBP50
Species	Human
Gene Type	protein-coding
Description	dynactin 2 (p50)
Other Description	50 kD dynein-associated polypeptide|50 kDa dynein-associated polypeptide|dynactin complex 50 kD subunit|dynactin complex 50 kDa subunit|dynactin subunit 2|epididymis secretory protein Li 77|p50 dynamitin
Swissprots	Q9BW17 Q86YN2 B2RBK5 Q13561
Accessions	EAW97027 EAW97028 EAW97029 Q13561 AK055682 BAG51555 AK096242 BAG53236 AK098794 AK222693 BAD96413 AK292364 BAF85053 AK314705 BAG37252 AY189155 AAO34395 BC000718 AAH00718 BC009468 AAH09468 BC014083 AAH14083 DB027733 DB569305 FJ224315 ACI46007 HQ447201 ADQ31688 U50733 AAC50423 XM_011537761 XP_011536063 XR_944481 NM_001261412 NP_001248341 NM_001261413 NP_001248342 NM_006400 NP_006391
Function	Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:8647893}. Membrane {ECO:0000269|PubMed:8647893}; Peripheral membrane protein {ECO:0000269|PubMed:8647893}.
Top Pathways	Huntington's disease, Vasopressin-regulated water reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Dynamitin full length protein - ab132555 from Abcam Category Protein Source Wheat germ Species Human

Human Dynamitin full length protein - ab174386 from Abcam Category Protein Source E. coli Species Human

Human Dynamitin full length protein - ab174453 from Abcam Category Protein Source E. coli Species Human

Dynactin 2 / Dynamitin Antibody Blocking Peptide - LS-E2027 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Dynactin 2 / Dynamitin Antibody Blocking Peptide - LS-E21379 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Dynactin Subunit 2/DCTN2/DCTN-50 Partial Recombinant Protein - H00010540-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Dynactin Subunit 2/DCTN2/DCTN-50 Recombinant Protein - H00010540-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Dynactin Subunit 2/DCTN2/DCTN-50 Protein - NBP2-23012 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human Dynactin Subunit 2/DCTN2/DCTN-50 Protein - NBP2-23011 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

Recombinant Human Dynactin Subunit 2/DCTN2/DCTN-50 Protein - NBP2-23010 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

DCTN2-Antibody-Center-Blocking-peptide - BP12893c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

DCTN2 protein (His tag) - 80R-3583 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

DCTN2 protein (His tag) - 80R-3572 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

DCTN2 protein (His tag) - 80R-3623 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Dynactin subunit 2 (1-401, His-tag) - AR51259PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

Dynactin subunit 2 (1-401, His-tag) - AR51259PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

Dynactin subunit 2 (1-403, His-tag) - AR51270PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Dynactin subunit 2 (1-403, His-tag) - AR51270PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Dynactin subunit 2 (1-406, His-tag) - AR51310PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

Dynactin subunit 2 (1-406, His-tag) - AR51310PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

Dynactin subunit 2 - H00010540-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Dynactin subunit 2 - H00010540-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Dynactin subunit 2 - H00010540-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Dynactin subunit 2 - H00010540-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

DCTN2, 1-401aa, Human, His tag, E.coli - 01-P2439 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

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