Gene Symbol | DOK2 |
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Entrez Gene | 9046 |
Alt Symbol | p56DOK, p56dok-2 |
Species | Human |
Gene Type | protein-coding |
Description | docking protein 2, 56kDa |
Other Description | docking protein 2|docking protein 2, 56kD|downstream of tyrosine kinase 2|p56(dok-2) |
Swissprots | O60496 Q8N5A4 |
Accessions | EAW63738 EAW63739 O60496 AF034970 AAC13265 AK226110 AK292126 BAF84815 AK296671 BAG59268 AL545478 BC032623 AAH32623 BQ067133 CB270269 DQ890550 ABM92167 DQ896808 ABM87807 XM_005273680 XP_005273737 XM_005273681 XP_005273738 XM_006716411 XP_006716474 XM_011544690 XP_011542992 NM_003974 NP_003965 NM_201349 |
Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity). {ECO:0000250}. |
Tissue Specificity | Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver. {ECO:0000269|PubMed:9478921}. |
Mouse/Human Phospho-DOK2 (Tyr299) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1487 from LifeSpan Bioscience
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Mouse/Human DOK2 ELISA Kit (Cell-Based ELISA) - LS-F2211 from LifeSpan Bioscience
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p56 Dok-2 Colorimetric Cell-Based ELISA Kit - CB5519 from Assay Biotechnology
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p56 Dok-2 (Phospho-Tyr299) Colorimetric Cell-Based ELISA Kit - CBP1531 from Assay Biotechnology
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Docking Protein 2 (DOK2), ELISA Kit - MBS9311615 from MyBioSource
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docking protein 2, 56kDa, ELISA Kit - MBS9318947 from MyBioSource
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Human DOK2 ELISA Kit - E012249 from Biobool
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Human Docking protein 2 ELISA Kit - EK2894 from Signalway Antibody
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anti-DOK-2 antibody - ARG52957 from Arigo Biolaboratories
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anti-DOK-2 antibody (Ready-to-Use) - ARG52958 from Arigo Biolaboratories
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Docking protein 2, ELISA Kit - MBS9426730 from MyBioSource
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