DOK2

Gene Symbol DOK2
Entrez Gene 9046
Alt Symbol p56DOK, p56dok-2
Species Human
Gene Type protein-coding
Description docking protein 2, 56kDa
Other Description docking protein 2|docking protein 2, 56kD|downstream of tyrosine kinase 2|p56(dok-2)
Swissprots O60496 Q8N5A4
Accessions EAW63738 EAW63739 O60496 AF034970 AAC13265 AK226110 AK292126 BAF84815 AK296671 BAG59268 AL545478 BC032623 AAH32623 BQ067133 CB270269 DQ890550 ABM92167 DQ896808 ABM87807 XM_005273680 XP_005273737 XM_005273681 XP_005273738 XM_006716411 XP_006716474 XM_011544690 XP_011542992 NM_003974 NP_003965 NM_201349
Function DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver. {ECO:0000269|PubMed:9478921}.

Dok-2 CRISPR/Cas9 KO Plasmid (h) - sc-405016 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 HDR Plasmid (h) - sc-405016-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 Double Nickase Plasmid (h) - sc-405016-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 Double Nickase Plasmid (h2) - sc-405016-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 CRISPR Activation Plasmid (h) - sc-405016-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 CRISPR Activation Plasmid (h2) - sc-405016-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 Lentiviral Activation Particles (h) - sc-405016-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 Lentiviral Activation Particles (h2) - sc-405016-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Dok-2 siRNA (h) - sc-35211 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-2 shRNA Plasmid (h) - sc-35211-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Dok-2 shRNA (h) Lentiviral Particles - sc-35211-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7428 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7428 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03905 from Sigma-Aldrich

Category miRNA

DOK2 siRNA (Human) - CRH5967 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOK2 - MBS8232499 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DOK2 (NM_003974.2) - SHH280281 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DOK2(NM_003974.2) - SHH013547 from Creative biogene

Category siRNA
Species Reactivities Human

Human DOK2 siRNA - orb266469 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DOK2 shRNA Plasmid (Human) - CHH5967 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DOK2 miRNA 3'UTR clone - MiUTR1H-02956 from Creative biogene

Species Reactivities Human
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