Gene Symbol | DOK2 |
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Entrez Gene | 9046 |
Alt Symbol | p56DOK, p56dok-2 |
Species | Human |
Gene Type | protein-coding |
Description | docking protein 2, 56kDa |
Other Description | docking protein 2|docking protein 2, 56kD|downstream of tyrosine kinase 2|p56(dok-2) |
Swissprots | O60496 Q8N5A4 |
Accessions | EAW63738 EAW63739 O60496 AF034970 AAC13265 AK226110 AK292126 BAF84815 AK296671 BAG59268 AL545478 BC032623 AAH32623 BQ067133 CB270269 DQ890550 ABM92167 DQ896808 ABM87807 XM_005273680 XP_005273737 XM_005273681 XP_005273738 XM_006716411 XP_006716474 XM_011544690 XP_011542992 NM_003974 NP_003965 NM_201349 |
Function | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation (By similarity). {ECO:0000250}. |
Tissue Specificity | Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver. {ECO:0000269|PubMed:9478921}. |
Human DOK2 full length protein - ab131830 from Abcam
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DOK2 Antibody Blocking Peptide - LS-E10576 from LifeSpan Bioscience
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DOK2 Antibody Blocking Peptide - LS-E9195 from LifeSpan Bioscience
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DOK2 Peptide - P2734 from Novus Biologicals
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DOK2-Antibody-C-term-Blocking-Peptide - BP7691b from Abgent, a WuXi AppTec company
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DOK2 peptide - orb218207 from Biorbyt
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DOK2 Blocking Peptide - 33R-7536 from Fitzgerald
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DOK2 (phospho-Tyr299) Blocking Peptide - abx063538 from Abbexa
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DOK2 / p56 dok2 - H00009046-P01-02 from Acris Antibodies
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DOK2 fusion protein - ag5356 from Proteintech Group
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DOK2 fusion protein - ag5218 from Proteintech Group
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p56Dok-2 (Phospho-Tyr299) Antibody Blocking Peptide - GWB-D34478 from Genway Biotech
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Recombinant Human DOK2, His-tagged - DOK2-28083TH from Creative Biomart
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DOK2 (pY299) Blocking Peptide - CBP2344 from Cohesion Biosciences
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Dok-2 (R293) Peptide - BS2637P from Bioworld Technology
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p-Dok-2 (Y299) Peptide - BS4786P from Bioworld Technology
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Recombinant Human Docking protein 2(DOK2) - CSB-YP007108HU CSB-EP007108HU CSB-BP007108HU CSB-MP007108HU from Cusabio
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Recombinant Human DOK2 Protein - H00009046-P01 from Novus Biologicals
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p56Dok-2(Phospho-Tyr299) antibody blocking peptide - 51278 from Signalway Antibody
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DOK2 Protein - abx163242 from Abbexa
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DOK2 / p56 dok2 - TP307621 from Acris Antibodies
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DOK2 Blocking Peptide - abx061694 from Abbexa
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DOK2-Antibody-N-term-Blocking-Peptide - BP7691a from Abgent, a WuXi AppTec company
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DOK2 Peptide, Human - M34GP04484H from Creative Peptides
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DOK2 Blocking Peptide - CBP7084 from Cohesion Biosciences
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