| Gene Symbol |
USP46
|
| Entrez Gene |
64854
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin specific peptidase 46
|
| Other Description |
deubiquitinating enzyme 46|ubiquitin carboxyl-terminal hydrolase 46|ubiquitin thioesterase 46|ubiquitin thiolesterase 46|ubiquitin-specific-processing protease 46
|
| Swissprots |
G8ACC7 B7Z3Y7 B7Z7S3 B7Z675 P62068
|
| Accessions |
EAX05434 EAX05435 P62068 AF070557 AK021861 AK021912 AK022614 BAB14133 AK024318 BAB14881 AK024345 AK096712 AK296493 BAH12373 AK299883 BAH13161 AK302438 BAH13709 BC037574 AAH37574 BP371221 BU620990 CN483539 DQ896764 ABM87763 EU176797 ABW03598 GU455414 ADV57651 NM_001134223 NP_001127695 NM_001286767 NP_001273696 NM_001286768 NP_001273697 NM_022832 NP_073743
|
| Function |
Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. {ECO:0000269|PubMed:19075014}.
|
| Tissue Specificity |
Broadly expressed. {ECO:0000269|PubMed:14715245}.
|