Gene Symbol | USP46 |
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Entrez Gene | 64854 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 46 |
Other Description | deubiquitinating enzyme 46|ubiquitin carboxyl-terminal hydrolase 46|ubiquitin thioesterase 46|ubiquitin thiolesterase 46|ubiquitin-specific-processing protease 46 |
Swissprots | G8ACC7 B7Z3Y7 B7Z7S3 B7Z675 P62068 |
Accessions | EAX05434 EAX05435 P62068 AF070557 AK021861 AK021912 AK022614 BAB14133 AK024318 BAB14881 AK024345 AK096712 AK296493 BAH12373 AK299883 BAH13161 AK302438 BAH13709 BC037574 AAH37574 BP371221 BU620990 CN483539 DQ896764 ABM87763 EU176797 ABW03598 GU455414 ADV57651 NM_001134223 NP_001127695 NM_001286767 NP_001273696 NM_001286768 NP_001273697 NM_022832 NP_073743 |
Function | Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. {ECO:0000269|PubMed:19075014}. |
Tissue Specificity | Broadly expressed. {ECO:0000269|PubMed:14715245}. |
USP46-Over-expression-Lysate - LY14845a from Abgent, a WuXi AppTec company
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USP46 293T Cell Transient Overexpression Lysate(Denatured) - H00064854-T01 from Acris Antibodies
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USP46 293 Cell Lysate - 402570 from ABBIOTEC
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USP46 Overexpression Lysate (Native) - NBL1-17667 from Novus Biologicals
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USP46 Over-expression Lysate Product - GWB-70974E from Genway Biotech
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Human USP46 Insect Cell Lysate (WB positive control) - 12976-HNCBL-300 from Sino Biological
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Human USP46 Insect Cell Lysate (WB positive control) - 12976-H21BL-300 from Sino Biological
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USP46 Overexpression Lysate (Denatured) - H00064854-T01 from Novus Biologicals
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Human USP46 Baculovirus-Insect Cells Transfected Lysate Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175217 from Biorbyt
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Human USP46 Baculovirus-Insect Cells Transfected Lysate Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175213 from Biorbyt
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Panoply™ Human USP46 Knockdown Stable Cell Line - CSC-DC017189 from Creative biogene
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