Gene Symbol | USP46 |
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Entrez Gene | 64854 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 46 |
Other Description | deubiquitinating enzyme 46|ubiquitin carboxyl-terminal hydrolase 46|ubiquitin thioesterase 46|ubiquitin thiolesterase 46|ubiquitin-specific-processing protease 46 |
Swissprots | G8ACC7 B7Z3Y7 B7Z7S3 B7Z675 P62068 |
Accessions | EAX05434 EAX05435 P62068 AF070557 AK021861 AK021912 AK022614 BAB14133 AK024318 BAB14881 AK024345 AK096712 AK296493 BAH12373 AK299883 BAH13161 AK302438 BAH13709 BC037574 AAH37574 BP371221 BU620990 CN483539 DQ896764 ABM87763 EU176797 ABW03598 GU455414 ADV57651 NM_001134223 NP_001127695 NM_001286767 NP_001273696 NM_001286768 NP_001273697 NM_022832 NP_073743 |
Function | Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. {ECO:0000269|PubMed:19075014}. |
Tissue Specificity | Broadly expressed. {ECO:0000269|PubMed:14715245}. |
Anti-USP46 antibody - ab155049 from Abcam
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Anti-USP46 antibody - ab88795 from Abcam
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Anti-USP46 antibody - ab116312 from Abcam
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Anti-USP46 Antibody (aa241-269, AP) - LS-C224590 from LifeSpan Bioscience
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Anti-USP46 Antibody (aa241-269, APC) - LS-C224589 from LifeSpan Bioscience
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Anti-USP46 Antibody (aa241-269, Biotin) - LS-C224591 from LifeSpan Bioscience
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Anti-USP46 Antibody (aa241-269, FITC) - LS-C224592 from LifeSpan Bioscience
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Anti-USP46 Antibody (aa241-269, Azide-free, HRP) - LS-C224593 from LifeSpan Bioscience
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Anti-USP46 Antibody (aa241-269, PE) - LS-C224594 from LifeSpan Bioscience
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Anti-USP46 Antibody (aa240-269) - LS-C326154 from LifeSpan Bioscience
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Anti-USP46 Antibody (aa241-269) - LS-C160398 from LifeSpan Bioscience
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USP46 Antibody - NBP2-20835 from Novus Biologicals
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USP46 Antibody - H00064854-B01P from Novus Biologicals
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USP46 Antibody - NBP1-82293 from Novus Biologicals
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USP46 Antibody (CL0364) - NBP2-30417 from Novus Biologicals
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USP46 Antibody - H00064854-A01 from Novus Biologicals
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Anti-USP46 antibody produced in rabbit - SAB2701340 from Sigma-Aldrich
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Anti-USP46 antibody produced in rabbit - HPA007288 from Sigma-Aldrich
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Anti-USP46 antibody produced in mouse - SAB1407903 from Sigma-Aldrich
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UBP46 Antibody - middle region (ARP59331_P050) - ARP59331_P050 from Aviva Systems Biology
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UBP46-Antibody-C-term - AP14161b from Abgent, a WuXi AppTec company
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UBP46 Antibody - C-terminal region (OAAB10460) - OAAB10460 from Aviva Systems Biology
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USP46 Polyclonal Antibody - A4939 from ABclonal
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USP46 antibody - 70R-21213 from Fitzgerald
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USP46 Antibody - abx003758 from Abbexa
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