Gene Symbol | USP46 |
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Entrez Gene | 64854 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 46 |
Other Description | deubiquitinating enzyme 46|ubiquitin carboxyl-terminal hydrolase 46|ubiquitin thioesterase 46|ubiquitin thiolesterase 46|ubiquitin-specific-processing protease 46 |
Swissprots | G8ACC7 B7Z3Y7 B7Z7S3 B7Z675 P62068 |
Accessions | EAX05434 EAX05435 P62068 AF070557 AK021861 AK021912 AK022614 BAB14133 AK024318 BAB14881 AK024345 AK096712 AK296493 BAH12373 AK299883 BAH13161 AK302438 BAH13709 BC037574 AAH37574 BP371221 BU620990 CN483539 DQ896764 ABM87763 EU176797 ABW03598 GU455414 ADV57651 NM_001134223 NP_001127695 NM_001286767 NP_001273696 NM_001286768 NP_001273697 NM_022832 NP_073743 |
Function | Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2. {ECO:0000269|PubMed:19075014}. |
Tissue Specificity | Broadly expressed. {ECO:0000269|PubMed:14715245}. |
Human USP46 full length protein - ab163894 from Abcam
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Human USP46 full length protein - ab177681 from Abcam
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Human USP46 protein fragment - ab163895 from Abcam
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USP46 Antibody Blocking Peptide - LS-E3030 from LifeSpan Bioscience
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USP46 Recombinant Protein - H00064854-P01 from Novus Biologicals
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USP46 Partial Recombinant Protein - H00064854-Q01 from Novus Biologicals
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UBP46-Antibody-C-term-Blocking-peptide - BP14161b from Abgent, a WuXi AppTec company
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Human USP46 protein (N-SUMO) - orb139848 from Biorbyt
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Human USP46 protein - orb139849 from Biorbyt
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USP46 protein (His tag) - 80R-3686 from Fitzgerald
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USP46 (1-366, His-tag) - AR51373PU-N from Acris Antibodies
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USP46 (1-366, His-tag) - AR51373PU-S from Acris Antibodies
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USP46 - H00064854-P01-10 from Acris Antibodies
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USP46 - H00064854-P01-25 from Acris Antibodies
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USP46 - H00064854-Q01-10 from Acris Antibodies
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USP46 - H00064854-Q01-25 from Acris Antibodies
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USP46, 1-366aa, Human, His tag, E.coli - 01-P2553 from ARP American Research Products
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USP46 fusion protein - Ag4330 from Proteintech Group
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USP46 fusion protein - ag5607 from Proteintech Group
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Recombinant Human USP46, SUMO tagged - USP46-7343H from Creative Biomart
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Recombinant Human USP46, None tagged - USP46-7344H from Creative Biomart
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Recombinant Human USP46, His-tagged - USP46-5057H from Creative Biomart
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Recombinant Human USP46, GST-tagged - USP46-3632H from Creative Biomart
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Recombinant Human ubiquitin specific peptidase 46, His-tagged - USP46-456H from Creative Biomart
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Human / Mouse USP46 Protein (SUMO Tag) - 12976-H21B-100 from Sino Biological
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