UCP3

Gene Symbol UCP3
Entrez Gene 7352
Alt Symbol SLC25A9
Species Human
Gene Type protein-coding
Description uncoupling protein 3 (mitochondrial, proton carrier)
Other Description mitochondrial uncoupling protein 3|solute carrier family 25 member 9
Swissprots O60475 Q96HL3 P55916
Accessions AAC18822 AAC51785 AAG02284 EAW74925 EAW74926 EAW74927 P55916 AF001787 AAC51369 AF011449 AAC51767 AK092685 BAG52595 AK290630 BAF83319 AK291889 BAF84578 AK309873 AW295096 BC008392 AAH08392 BU618868 DA876282 U82818 AAC51356 U84763 AAC51367 NM_003356 NP_003347 NM_022803 NP_073714
Function UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
Subcellular Location Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity Only in skeletal muscle and heart. Is more expressed in glycolytic than in oxidative skeletal muscles. {ECO:0000269|PubMed:9196039}.

UCP3 (C-20) - sc-7756 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UCP3 (C-20): sc-7756. Western blot analysis of UCP3 expression in rat skeletal muscle (A) and mouse heart (B) tissue extracts.

UCP3 (D-20) - sc-31385 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UCP3 (D-20): sc-31385. Western blot analysis of UCP3 expression in A10 (A) and Sol8 (B) whole cell lysates and rat skeletal muscle (C) and mouse heart (D) tissue extracts.

UCP3 (E-18) - sc-31387 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UCP3 (E-18): sc-31387. Western blot analysis of UCP3 expression in rat skeletal muscle (A) and mouse heart (B) tissue extracts.

Anti-UCP3 antibody - ab3477 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab3477 staining UCP3 in differentiated cardiac ventricular cells by Flow Cytometry. Cells were fixed with paraformaldehyde and permeabilized with permeabilization buffer. The sample was incubated with the primary antibody (1/400) for 12 hours at 4°C. An Allophycocyanin-conjugated goat polyclonal anti-rabbit IgG (1/1000) was used as the secondary antibody.Gating Strategy: Isotype negative control (white).See Abreview

Anti-UCP3 antibody - ab10985 from Abcam

Prices $382.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab10985 (2µg/ml) staining UCP3 in human skeletal muscle using an automated system (DAKO Autostainer Plus). Using this protocol there is strong cytoplasmic staining of myocytes.Sections were rehydrated and antigen retrieved with the Dako 3 in 1 AR buffer EDTA pH 9.0 in a DAKO PT link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 mins. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 min and detected with Dako Envision Flex amplification kit for 30 minutes. Colorimetric detection was completed with Diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that, for manual staining, optimization of primary antibody concentration and incubation time is recommended. Signal amplification may be required.

Anti-UCP3 antibody - ab180643 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of MCF7 cells using ab180643. Blue DAPI for nuclear staining.

Anti-UCP3 antibody - ab125830 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCP3 antibody [mAbcam61299] - ab61299 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone mAbcam61299
Anti-UCP3 antibody [mAbcam61299] (ab61299) at 10 µg/ml + Skeletal Muscle (Human) Tissue Lysate - adult normal tissue (ab29330) at 10 µgSecondaryGoat polyclonal Secondary Antibody to Mouse IgM - H&L (HRP), pre-adsorbed at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-UCP3 Antibody - LS-C10953 from LifeSpan Bioscience

Prices $515.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-UCP3 Antibody - LS-C10954 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-UCP3 Antibody (aa295-308) - LS-C10958 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-UCP3 Antibody (C-Terminus) - LS-C10957 from LifeSpan Bioscience

Prices $575.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-UCP3 Antibody (aa110-124) - LS-C191367 from LifeSpan Bioscience

Prices $740.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-UCP3 Antibody (C-Terminus) - LS-C189283 from LifeSpan Bioscience

Prices $425.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-UCP3 Antibody (aa125-175) - LS-C148360 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of UCP3 in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart using LS-C148360 at 1.0 ug/ml.

Anti-UCP3 Antibody (Arg308) - LS-C177228 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of UCP3 (R308) pAb in extracts from Jurkat cells.

Anti-UCP3 Antibody (aa259-308) - LS-C200043 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of UCP3 antibody in extracts from Jurkat cells.

Anti-UCP3 Antibody - LS-C192926 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of skeletal muscle cell and SGC-7901 cell line, using UCP3 antibody.

Anti-UCP3 Antibody - LS-C331518 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human liver cancer using UCP3 antibody at dilution of 1:200 (x400 lens).

UCP3 Antibody - NBP2-24608 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: UCP3 Antibody [NBP2-24608] - analysis of UCP3 in human heart lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse heart and 4) rat heart using this antibody at 1.0 ug/ml.

UCP3 Antibody - NBP2-20797 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: UCP3 Antibody [NBP2-20797] - A. 30 ug RD whole cell lysate/extract 12 % SDS-PAGE UCP3 antibody dilution: 1:1000

UCP3 Antibody - NBP1-51195 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: UCP3 Antibody [NBP1-51195] Extracts from Jurkat cells

UCP-3 Polyclonal Antibody - bs-1934R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UCP3 antibody produced in rabbit - SAB4300721 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-UCP-3 antibody produced in rabbit - U7757 from Sigma-Aldrich

Prices $326.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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