XPA

Gene Symbol XPA
Entrez Gene 7507
Alt Symbol XP1, XPAC
Species Human
Gene Type protein-coding
Description xeroderma pigmentosum, complementation group A
Other Description DNA repair protein complementing XP-A cells|excision repair-controlling|mutant xeroderma pigmentosum complementation group A|xeroderma pigmentosum group A-complementing protein
Swissprots P23025 Q6LCW7 Q6LD02 Q5T1U9
Accessions AAA92883 AAB60404 AAM18969 EAW58855 P23025 AI961077 AL531629 BC014965 AAH14965 BT019518 AAV38325 CB155090 D14533 BAA03403 DQ893624 ABM84550 DQ895423 ABM86349 HG502281 KC899693 AHF45877 S89853 AAB21861 XM_006717278 XP_006717341 XM_011518988 XP_011517290 XR_929839 NM_000380 NP_000371 NR_027302
Function Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation. {ECO:0000269|PubMed:19197159}.
Subcellular Location Nucleus {ECO:0000269|PubMed:1918083, ECO:0000269|PubMed:19197159, ECO:0000269|PubMed:20304803}.
Tissue Specificity Expressed in various cell lines and in skin fibroblasts. {ECO:0000269|PubMed:1918083, ECO:0000269|PubMed:8543191}.
Top Pathways Nucleotide excision repair

Human-XPA-cDNA-Clone - DC03979 from Abgent, a WuXi AppTec company

Prices $368.55
Sizes 10 µg
Species Human
Accession BC014965

XPA - MBS1267592 from MyBioSource

Species Human
Accession BC014965

Human XPA ORF Clone(NM_000380.3) - CDCL181418 from Creative Biomart

Species Human
Accession NM_000380.3

human XPA ORF clone - CDCH101778 from Creative Biomart

Species Human
Accession NM_000380

human XPA ORF clone - CDCH101779 from Creative Biomart

Species Human
Accession NM_000380

Human XPA ORF Clone (BC014965) - CDCS405624 from Creative biogene

Species Human
Accession P23025

Human XPA ORF clone (BC014965) - CDCB159576 from Creative biogene

Species Human
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