XPA

Gene Symbol XPA
Entrez Gene 7507
Alt Symbol XP1, XPAC
Species Human
Gene Type protein-coding
Description xeroderma pigmentosum, complementation group A
Other Description DNA repair protein complementing XP-A cells|excision repair-controlling|mutant xeroderma pigmentosum complementation group A|xeroderma pigmentosum group A-complementing protein
Swissprots P23025 Q6LCW7 Q6LD02 Q5T1U9
Accessions AAA92883 AAB60404 AAM18969 EAW58855 P23025 AI961077 AL531629 BC014965 AAH14965 BT019518 AAV38325 CB155090 D14533 BAA03403 DQ893624 ABM84550 DQ895423 ABM86349 HG502281 KC899693 AHF45877 S89853 AAB21861 XM_006717278 XP_006717341 XM_011518988 XP_011517290 XR_929839 NM_000380 NP_000371 NR_027302
Function Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation. {ECO:0000269|PubMed:19197159}.
Subcellular Location Nucleus {ECO:0000269|PubMed:1918083, ECO:0000269|PubMed:19197159, ECO:0000269|PubMed:20304803}.
Tissue Specificity Expressed in various cell lines and in skin fibroblasts. {ECO:0000269|PubMed:1918083, ECO:0000269|PubMed:8543191}.
Top Pathways Nucleotide excision repair

XPA CRISPR/Cas9 KO Plasmid (h) - sc-401483 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA HDR Plasmid (h) - sc-401483-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA Double Nickase Plasmid (h) - sc-401483-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA Double Nickase Plasmid (h2) - sc-401483-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA CRISPR Activation Plasmid (h) - sc-401483-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA CRISPR Activation Plasmid (h2) - sc-401483-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA Lentiviral Activation Particles (h) - sc-401483-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA Lentiviral Activation Particles (h2) - sc-401483-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

XPA siRNA (h) - sc-36853 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XPA shRNA Plasmid (h) - sc-36853-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XPA shRNA (h) Lentiviral Particles - sc-36853-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

XPA RNAi - H00007507-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU023141 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22972 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22972 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03947 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03947

XPA siRNA (Human) - CRH5131 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

XPA - MBS8209620 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human XPA (NM_000380.3) - SHH447940 from Creative biogene

Category siRNA
Species Reactivities Human

Human XPA siRNA - orb265633 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

XPA shRNA Plasmid (Human) - CHH5131 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

XPA miRNA 3'UTR clone - MiUTR3H-11678 from Creative biogene

Species Reactivities Human
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