HTN3

Gene Symbol	HTN3
Entrez Gene	3347
Alt Symbol	HIS2, HTN2, HTN5
Species	Human
Gene Type	protein-coding
Description	histatin 3
Other Description	PB|basic histidine-rich protein|histatin 5|histatin-3|histatin-4|histatin-5|histatin-6|histatin-7|histatin-8|histatin-9|histidine-rich protein 3|hst
Swissprots	Q16243 P15516 Q502Z1
Accessions	AAA02746 AAB32411 EAX05606 P15516 BC009791 AAH09791 BC095438 AAH95438 BP332860 CB957931 DQ892864 ABM83790 DQ896113 ABM87112 M18372 AAA51830 M26665 AAA58646 NM_000200 NP_000191
Function	Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9. {ECO:0000269|PubMed:11179305, ECO:0000269|PubMed:8945538}.
Subcellular Location	Secreted {ECO:0000269|PubMed:14966203}. Note=Secreted by serous acinar and demilune cells.
Top Pathways	Salivary secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-HTN3-cDNA-Clone - DC02773 from Abgent, a WuXi AppTec company Prices $68.85 Sizes 10 µg Species Human Accession BC009791

HTN3 - MBS1275581 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC009791

Human HTN3/Histatin-3 Gene ORF cDNA clone in cloning vector - HG13627-G from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13627-NM from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13627-CF from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13627-CM from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, N-His tag - HG13627-NH from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13627-CY from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, C-His tag - HG13627-CH from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid - HG13627-UT from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13627-NY from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13627-ACG from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13627-ACR from Sino Biological Species Human

Human HTN3/Histatin-3 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13627-NF from Sino Biological Species Human

Human HTN3 ORF Clone (BC009791) - CDCS405497 from Creative biogene Species Human Accession P15516

Human HTN3 ORF clone (BC009791) - CDCB159620 from Creative biogene Species Human

Human HTN3 Gene cDNA Clone - orb143640 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

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